Protein Domain : IPR020444

Type:  Family Name:  Interleukin-24
Description:  Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells. Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26 []. It has been proposed, based on the expression pattern of IL-24 and its receptors, that the cytokine may play a role in epidermal functions, such as wound healing []. IL-24 has also been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent []. This entry represents interleukin-24. Short Name:  IL-24

0 Child Features

2 Contains

DB identifier Type Name
IPR012351 Domain Four-helical cytokine, core
IPR020423 Conserved_site Interleukin-10, conserved site

1 Cross References

Identifier
PR01937

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR020443 Family Interleukin-10/19/20/24/26 family

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11929132
            15667561
            14508078