Protein Domain : IPR011870

Type:  Family Name:  Lysine biosynthesis enzyme LysX
Description:  The family of proteins found in this family include the characterised LysX from Thermus thermophilus[] which is part of a well-organised lysine biosynthesis gene cluster []. LysX is believed to carry out an ATP-dependent acylation of the amino group of alpha-aminoadipate in the prokaryotic version of the fungal AAA lysine biosynthesis pathway. No species having a sequence in this family contains the elements of the more common diaminopimelate lysine biosythesis pathway, and none has been shown to be a lysine auxotroph. These sequences have mainly recieved the name of the related enzyme, "ribosomal protein S6 modification protein RimK". RimK has been characterised in Escherichia coli, and acts by ATP-dependent condensation of S6 with glutamate residues []. Short Name:  LysX_arch

0 Child Features

3 Contains

DB identifier Type Name
IPR016185 Domain Pre-ATP-grasp domain
IPR013816 Domain ATP-grasp fold, subdomain 2
IPR013651 Domain ATP-grasp fold, RimK-type

1 Cross References

Identifier
TIGR02144

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003824 IPR011870
GO:0005524 IPR011870
GO:0009085 IPR011870

3 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR011870
GO:0005524 IPR011870
GO:0009085 IPR011870

1 Parent Features

DB identifier Type Name
IPR004666 Family Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX

0 Proteins

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12963379
            10613839
            2570347