GO Term : GO:0004357 glutamate-cysteine ligase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0004357 83292  
OntologyAnnotation GO:0004357 83292 GO
GOAnnotation GO:0004357 101407  
OntologyAnnotation GO:0004357 101407 GO
OntologyAnnotation GO:0004357 evm.model.supercontig_74.44 GO
GOAnnotation GO:0004357 evm.TU.supercontig_74.44  
GOAnnotation GO:0004357 30190.t000450  
OntologyAnnotation GO:0004357 30190.m011214 GO
GOAnnotation GO:0004357 30343.t000001  
OntologyAnnotation GO:0004357 30343.m000024 GO
GOAnnotation GO:0004357 48769.t000001  
OntologyAnnotation GO:0004357 48769.m000014 GO
GOAnnotation GO:0004357 Cucsa.303150  
OntologyAnnotation GO:0004357 Cucsa.303150.1 GO
OntologyAnnotation GO:0004357 Cucsa.303150.2 GO
OntologyAnnotation GO:0004357 orange1.1g014287m GO
OntologyAnnotation GO:0004357 orange1.1g015997m GO
OntologyAnnotation GO:0004357 orange1.1g011318m GO
OntologyAnnotation GO:0004357 orange1.1g014295m GO
OntologyAnnotation GO:0004357 orange1.1g011314m GO
OntologyAnnotation GO:0004357 orange1.1g011330m GO
GOAnnotation GO:0004357 orange1.1g010751m.g  
OntologyAnnotation GO:0004357 orange1.1g010751m GO
OntologyAnnotation GO:0004357 orange1.1g016072m GO
OntologyAnnotation GO:0004357 AT4G23100.1 GO
GOAnnotation GO:0004357 AT4G23100  
OntologyAnnotation GO:0004357 AT4G23100.2 GO
OntologyAnnotation GO:0004357 AT4G23100.3 GO
OntologyAnnotation GO:0004357 Thhalv10024917m GO
OntologyAnnotation GO:0004357 Thhalv10024912m GO

8 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016874 ligase activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016881 acid-amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0004357 glutamate-cysteine ligase activity Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.
GO:0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

15 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016881 GO:0004357
part of GO:0008150 GO:0004357
is_a GO:0016874 GO:0004357
part of GO:0008152 GO:0004357
is_a GO:0003674 GO:0004357
is_a GO:0016879 GO:0004357
is_a GO:0003824 GO:0004357
regulates GO:0004357 GO:0035227
regulates GO:0004357 GO:0035227
negatively regulates GO:0004357 GO:0035228
negatively regulates GO:0004357 GO:0035228
regulates GO:0004357 GO:0035228
positively regulates GO:0004357 GO:0035229
positively regulates GO:0004357 GO:0035229
regulates GO:0004357 GO:0035229

4 Synonyms

Name Type
gamma-glutamylcysteine synthetase activity synonym
gamma-glutamyl-L-cysteine synthetase activity synonym
L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity synonym
gamma-glutamylcysteinyl synthetase activity synonym