Protein Domain : IPR013131

Type:  Domain Name:  Mannitol dehydrogenase, N-terminal
Description:  Mannitol-1-phosphate 5-dehydrogenase catalyses the NAD-dependent reduction of mannitol-1-phosphate to fructose-6-phosphate [] as part of the phosphoenolpyruvate-dependent phosphotransferase system (PTS). The PTS facilitates the vectorial translocation of metabolisable carbohydrates to formthe corresponding sugar phosphates, which are then converted to glycolytic intermediates []. Mannitol 2-dehydrogenase catalyses the NAD-dependent reduction of mannitol to fructose [].Several dehydrogenases have been shown [] to be evolutionary related, including mannitol-1-phosphate 5-dehydrogenase () (gene mtlD), mannitol 2-dehydrogenase () (gene mtlK); mannonate oxidoreductase () (fructuronate reductase) (gene uxuB); Escherichia colihypothetical proteins ydfI and yeiQ; and yeast hypothetical protein YEL070w. This domain has a Rossmann-type fold. Short Name:  Mannitol_DH_N
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0 Child Features

0 Contains

1 Cross References

Identifier
PF01232

2 Found Ins

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR000669 Family Mannitol dehydrogenase

2 GO Annotations

GO Term Gene Name
GO:0016491 IPR013131
GO:0055114 IPR013131

2 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR013131
GO:0055114 IPR013131

0 Parent Features

25 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
213628 C1N0F0 PAC:27340551 Micromonas pusilla CCMP1545 560  
125487 PAC:27340467 Micromonas pusilla CCMP1545 647  
62890 C1FJR7 PAC:27399803 Micromonas sp RCC299 570  
62889 C1FJR8 PAC:27399968 Micromonas sp RCC299 634  
Araha.11756s0241.1.p PAC:28856458 Arabidopsis halleri 386  
Brdisv1pangenome1006393m.p PAC:33619083 Brachypodium distachyon Pangenome 298  
Brdisv1pangenome1007266m.p PAC:33641287 Brachypodium distachyon Pangenome 970  
Brdisv1pangenome1006906m.p PAC:33655329 Brachypodium distachyon Pangenome 507  
Brdisv1pangenome1008114m.p PAC:33620598 Brachypodium distachyon Pangenome 537  
Brdisv1pangenome1009028m.p PAC:33624396 Brachypodium distachyon Pangenome 496  
Brdisv1pangenome1009902m.p PAC:33607277 Brachypodium distachyon Pangenome 382  
Brdisv1BdTR8i1044470m.p PAC:34242240 Brachypodium distachyon BdTR8i 298  
Brdisv1BdTR12c1040000m.p PAC:34405525 Brachypodium distachyon BdTR12c 458  
Brdisv1BdTR11G1006512m.p PAC:34614623 Brachypodium distachyon BdTR11g 388  
Brdisv1BdTR11A1045451m.p PAC:35695124 Brachypodium distachyon BdTR11a 493  
Brdisv1BdTR11A1043397m.p PAC:35696690 Brachypodium distachyon BdTR11a 573  
Brdisv1BdTR11A1042172m.p PAC:35690172 Brachypodium distachyon BdTR11a 558  
Brdisv1BdTR11A1040096m.p PAC:35695183 Brachypodium distachyon BdTR11a 507  
Brdisv1BdTR11A1040738m.p PAC:35690380 Brachypodium distachyon BdTR11a 382  
Brdisv1BdTR11A1042114m.p PAC:35688106 Brachypodium distachyon BdTR11a 970  
Brdisv1BdTR11A1037380m.p PAC:35684561 Brachypodium distachyon BdTR11a 523  
Thint.V1707100.1.p PAC:40758134 Thinopyrum intermedium 445  
Nycol.A03562.1.p PAC:44495327 Nymphaea colorata 370  
36037.m000014 B9TL38 PAC:16826851 Ricinus communis 315  
36037.m000014 B9TL38 PAC:16826851 Ricinus communis 315  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1322373
            8254318
            1904856