Protein Domain : IPR002078

Type:  Domain Name:  RNA polymerase sigma factor 54 interaction domain
Description:  Some bacterial regulatory proteins activate the expression of genes from promoters recognised by core RNA polymerase associated with the alternativesigma-54 factor. These have a conserved domain of about 230 residues involved in the ATP-dependent [, ] interaction with sigma-54. About half of the proteins in which this domain is found (algB, dcdT, flbD, hoxA, hupR1, hydG, ntrC, pgtA and pilR) belong to signal transduction two-component systems [] and possess a domain that can be phosphorylated by a sensor-kinase protein in their N-terminal section. Almost all of these proteins possess a helix-turn-helix DNA-binding domain in their C-terminal section.The domain which interacts with the sigma-54 factor has an ATPase activity. This may be required to promote a conformational change necessary for the interaction []. The domain contains an atypical ATP-binding motif A (P-loop) as well as a form of motif B. The two ATP-binding motifs are located in the N-terminal section of the domain. Short Name:  Sigma_54_int
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF00158
PS50045

8 Found Ins

DB identifier Type Name
IPR010113 Family Nif-specific regulatory protein
IPR014317 Family Transcription activator PspF
IPR010114 Family Signal transduction response regulator, nitrogen regulation NR(I)
IPR014264 Family Signal transduction response regulator, PEP-CTERM system, putative
IPR012704 Family Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR
IPR014251 Family Sporulation protease LonB
IPR014252 Family Sporulation protease LonC
IPR017183 Family Sigma54-dependent transcriptional activator, RtcR

3 GO Annotations

GO Term Gene Name
GO:0005524 IPR002078
GO:0008134 IPR002078
GO:0006355 IPR002078

3 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR002078
GO:0008134 IPR002078
GO:0006355 IPR002078

0 Parent Features

50 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
30797.m000025 B9TKY4 PAC:16824623 Ricinus communis 167  
32291.m000022 B9THZ1 PAC:16825371 Ricinus communis 276  
32308.m000023 B9TE40 PAC:16825384 Ricinus communis 178  
32670.m000026 PAC:16825516 Ricinus communis 138  
53335 I0YYF9 PAC:27386620 Coccomyxa subellipsoidea C-169 862  
45481 C1MR89 PAC:27346680 Micromonas pusilla CCMP1545 792  
Cre12.g512400.t1.1 A0A2K3D2H1 PAC:30792780 Chlamydomonas reinhardtii 840  
Medtr0681s0010.1 A0A072TQ10 PAC:31092022 Medicago truncatula 587  
Medtr1101s0010.1 A0A072TPE0 PAC:31106036 Medicago truncatula 313  
Traes_5AL_04D3E97F0.3 PAC:32012710 Triticum aestivum 212  
Traes_5AL_04D3E97F0.4 PAC:32012712 Triticum aestivum 212  
Traes_5AL_04D3E97F0.2 PAC:32012711 Triticum aestivum 212  
Traes_5DL_743B870D9.3 PAC:31886618 Triticum aestivum 210  
Traes_5DL_743B870D9.4 PAC:31886619 Triticum aestivum 210  
Sphfalx0142s0021.1.p PAC:32627993 Sphagnum fallax 1022  
Sphfalx0042s0145.1.p PAC:32612956 Sphagnum fallax 919  
Pp3c20_16700V3.1.p A0A2K1IVH3 PAC:32945574 Physcomitrium patens 1032  
Pp3c20_16700V3.2.p A0A2K1IVH3 PAC:32945575 Physcomitrium patens 1032  
Pp3s32_490V3.1.p PAC:32948359 Physcomitrium patens 481  
Pp3s30_420V3.1.p PAC:32948528 Physcomitrium patens 364  
Pp3s30_700V3.1.p PAC:32948532 Physcomitrium patens 1653  
Pp3s30_90V3.1.p PAC:32948503 Physcomitrium patens 875  
Pp3s34_430V3.1.p PAC:32948293 Physcomitrium patens 569  
Pp3s58_320V3.1.p PAC:32929816 Physcomitrium patens 2487  
Dusal.0055s00005.1.p PAC:33187639 Dunaliella salina 705  
Brdisv1Tek-41038808m.p PAC:33490908 Brachypodium distachyon Tek-4 451  
Brdisv1pangenome1007120m.p PAC:33620214 Brachypodium distachyon Pangenome 249  
Brdisv1BdTR11A1049410m.p PAC:35693031 Brachypodium distachyon BdTR11a 407  
Brdisv1BdTR11A1040958m.p PAC:35694592 Brachypodium distachyon BdTR11a 1387  
Brdisv1BdTR11A1041930m.p PAC:35687672 Brachypodium distachyon BdTR11a 543  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2694934
            1534752
            8407777
            2041769