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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. |
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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0006470
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protein dephosphorylation
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The process of removing one or more phosphoric residues from a protein. |
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GO:0008138
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protein tyrosine/serine/threonine phosphatase activity
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Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. |
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GO:0016311
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dephosphorylation
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The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. |
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GO:0016791
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phosphatase activity
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Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
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GO:0006796
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phosphate-containing compound metabolic process
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The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0016788
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hydrolase activity, acting on ester bonds
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Catalysis of the hydrolysis of any ester bond. |
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GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
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GO:0042578
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phosphoric ester hydrolase activity
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Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. |
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GO:0004721
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phosphoprotein phosphatase activity
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Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. |
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GO:0006464
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cellular protein modification process
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The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). |
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GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
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GO:0009966
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regulation of signal transduction
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Any process that modulates the frequency, rate or extent of signal transduction. |
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GO:0043412
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macromolecule modification
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The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0001932
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regulation of protein phosphorylation
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Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0043086
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negative regulation of catalytic activity
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Any process that stops or reduces the activity of an enzyme. |
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GO:0045859
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regulation of protein kinase activity
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Any process that modulates the frequency, rate or extent of protein kinase activity. |
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GO:0044260
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cellular macromolecule metabolic process
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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
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GO:0042325
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regulation of phosphorylation
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Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. |
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GO:0044267
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cellular protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0017017
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MAP kinase tyrosine/serine/threonine phosphatase activity
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Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate. |
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GO:0006793
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phosphorus metabolic process
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The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). |
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GO:0045936
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negative regulation of phosphate metabolic process
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Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. |
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GO:0008150
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biological_process
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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
