| Type: | Domain | Name: | Sulfatase |
| Description: | This entry represents a domain found in sulphatases. Sulphatases are enzymes that hydrolyze various sulphate esters. The sequence of different types of sulphatases are available and have shown to be structurally related [, , ]; these include:arylsulphatase A (ASA), a lysosomal enzyme which hydrolyses cerebroside sulphate; arylsulphatase B (ASB), which hydrolyses the sulphate ester group from N-acetylgalactosamine 4-sulphate residues of dermatan sulphate; arylsulphatase C (ASD) and E (ASE);steryl-sulphatase (STS), a membrane bound microsomal enzyme which hydrolyses 3-beta-hydroxy steroid sulphates;iduronate 2-sulphatase precursor (IDS), a lysosomal enzyme that hydrolyses the 2-sulphate groups from non-reducing-terminal iduronic acid residues in dermatan sulphate and heparan sulphate;N-acetylgalactosamine-6-sulphatase , which hydrolyses the 6-sulphate groups of the N-acetyl-d-galactosamine 6-sulphate units of chondroitin sulphate and the D-galactose 6-sulphate units of keratan sulphate;glucosamine-6-sulphatase (G6S), which hydrolyses the N-acetyl-D-glucosamine 6-sulphate units of heparan sulphate and keratan sulphate;N-sulphoglucosamine sulphohydrolase (sulphamidase), the lysosomal enzyme that catalyses the hydrolysis of N-sulpho-d-glucosamine into glucosamine and sulphate;sea urchin embryo arylsulphatase ;green algae arylsulphatase , which plays an important role in the mineralisation of sulphates;and arylsulphatase from Escherichia coli(aslA), Klebsiella aerogenes(gene atsA) and Pseudomonas aeruginosa(gene atsA). | Short Name: | Sulfatase |
| DB identifier | Type | Name |
|---|---|---|
| IPR012160 | Family | Membrane sulfatase, HI1246-related |
| IPR012083 | Family | Arylsulfatase |
| IPR017785 | Family | Choline-sulfatase |
| IPR012159 | Family | Inner membrane protein YejM |
| IPR014615 | Family | Extracellular sulfatase |
| IPR012251 | Family | N-acetylglucosamine-6-sulfatase |
| IPR015981 | Family | N-acetylglucosamine-6-sulfatase, eukaryotic |
| IPR020881 | Family | Phosphoglycerol transferase I |
