1 Child Features
DB identifier | Type | Name |
---|---|---|
IPR023941 | Family | Glutathione-regulated potassium-efflux system protein KefC |
3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0015079 | IPR006036 |
GO:0006813 | IPR006036 |
GO:0005886 | IPR006036 |
Type: | Family | Name: | Potassium uptake protein TrkA |
Description: | The Trk system is a low to medium affinity potassium uptake system, widely found in both in bacteria and archaea, where the uptake of K(+) is believed to be linked to H(+) symport []. The core Trk system consists of two proteins, the integral membrane K(+)-translocating protein TrkH (or TrkG), and the NAD-binding peripheral membrane protein TrkA [, ]. In Escherichia colithe activity of TrkH is dependent on the ATP-binding protein SapD (also known as TrkE) which is part of the SapABCDF ABC transporter of unkown function. Not all Trk systems are dependent on SapD however - it is thought that these may utilise ATP-binding proteins from other ABC transporters [].Sequence analysis of TrkA reveals that the protein consists of 2 tandemly arrayed halves that are 22% identical, a situation that might have arisen through gene duplication. TrkA also exhibits similarity to other Escherichia coliproteins [], in particular KefC, a glutathione- regulated efflux protein [], and to various dehydrogenase proteins that possess NAD+binding sites. | Short Name: | K_uptake_TrkA |
DB identifier | Type | Name |
---|---|---|
IPR023941 | Family | Glutathione-regulated potassium-efflux system protein KefC |
GO Term | Gene Name |
---|---|
GO:0015079 | IPR006036 |
GO:0006813 | IPR006036 |
GO:0005886 | IPR006036 |