Protein Domain : IPR002321

Type:  Family Name:  Cytochrome c, class II
Description:  Cytochromes c (cytC) can be defined as electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes. Ambler [] recognised four classes of cytC. Class II includes the high-spin cytC' and a number of low-spin cytochromes, e.g. cyt c-556. The haem-attachment site is close to the C terminus. The cytC' are capable of binding such ligands as CO, NO or CN(-), albeit with rate and equilibriumconstants 100 to 1,000,000-fold smaller than other high-spin haemoproteins []. This, coupled with its relatively low redox potential, makes itunlikely that cytC' is a terminal oxidase. Thus cytC' probably functions as an electron transfer protein []. The 3D structures of a number of cytC' have been determined. The molecule usually exists as a dimer, each monomer folding as a four-alpha-helix bundleincorporating a covalently-bound haem group at the core []. The Chromatium vinosumcytC' exhibits dimer dissociation upon ligand binding []. Short Name:  Cyt_c_II

1 Child Features

DB identifier Type Name
IPR012127 Family Cytochrome c prime

0 Contains

2 Cross Referencess

Identifier
PF01322
PS51009

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005506 IPR002321
GO:0009055 IPR002321
GO:0020037 IPR002321

3 Ontology Annotations

GO Term Gene Name
GO:0005506 IPR002321
GO:0009055 IPR002321
GO:0020037 IPR002321

1 Parent Features

DB identifier Type Name
IPR010980 Family Cytochrome c/b562

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Potri.014G063400.1 A0A2K1XRA8 PAC:27033227 Populus trichocarpa 242  
Cre13.g564151.t1.1 A0A2K3CZ48 PAC:30784350 Chlamydomonas reinhardtii 2403  
Cre02.g095108.t1.1 A0A2K3E1R9 PAC:30785074 Chlamydomonas reinhardtii 251  
Potri.014G063400.1.p A0A2K1XRA8 PAC:37267272 Populus trichocarpa 242  
Pum0377s0004.1.p A0A1X6NXK5 PAC:38016253 Porphyra umbilicalis 562  
Pum0399s0004.1.p A0A1X6NW63 PAC:38017753 Porphyra umbilicalis 794  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1646016
            1646017
            1646027
            8230224