Protein Domain : IPR012127

Type:  Family Name:  Cytochrome c prime
Description:  Cytochromes c (cytC) can be defined as electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes. Ambler [] recognised four classes of cytC. Class II includes the high-spin cytC' and a number of low-spin cytochromes, e.g. cyt c-556. The haem-attachment site is close to the C terminus. The cytC' are capable of binding such ligands as CO, NO or CN(-), albeit with rate and equilibrium constants 100 to 1,000,000-fold smaller than other high-spin haemoproteins []. This, coupled with its relatively low redox potential, makes it unlikely that cytC' is a terminal oxidase. Thus cytC' probably functions as an electron transfer protein []. The 3D structures of a number of cytC' have been determined. The molecule usually exists as a dimer, each monomer folding as a four-alpha-helix bundleincorporating a covalently-bound haem group at the core []. The Chromatium vinosumcytC' exhibits dimer dissociation upon ligand binding []. Short Name:  Cyt_c_prime
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1 Child Features

DB identifier Type Name
IPR015984 Family Cytochrome c prime, subgroup

0 Contains

1 Cross References

Identifier
PIRSF000027

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0005506 IPR012127
GO:0009055 IPR012127
GO:0020037 IPR012127
GO:0042597 IPR012127

4 Ontology Annotations

GO Term Gene Name
GO:0005506 IPR012127
GO:0009055 IPR012127
GO:0020037 IPR012127
GO:0042597 IPR012127

1 Parent Features

DB identifier Type Name
IPR002321 Family Cytochrome c, class II

0 Proteins

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1646016
            1646017
            1646027
            8230224