Protein Domain : IPR002069

Type:  Family Name:  Interferon gamma
Description:  Interferon gamma (IFN-gamma) is produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma shows antiviral activity and has important immunoregulatory functions. It is a potent activator of microphages and had antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons.The crystal structures of a number IFN-gamma proteins have been solved, including bovine interferon-gamma at 2.0-A [] and human IFN-gamma at 2.9-A []. Short Name:  Interferon_gamma
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0 Child Features

1 Contains

DB identifier Type Name
IPR012351 Domain Four-helical cytokine, core

4 Cross Referencess

Identifier
PTHR11419
PF00714
PIRSF001936
PD002435

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005133 IPR002069
GO:0006955 IPR002069
GO:0005576 IPR002069

3 Ontology Annotations

GO Term Gene Name
GO:0005133 IPR002069
GO:0006955 IPR002069
GO:0005576 IPR002069

0 Parent Features

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1Gaz-81031589m.p PAC:33819665 Brachypodium distachyon Gaz-8 67  
Phvul.007G051300.1.p V7BCA5 PAC:37167081 Phaseolus vulgaris 669  
PvUI111.07G052000.1.p PAC:42837097 Phaseolus vulgaris UI111 669  
Pl07G0000055200.1.v1 PAC:44361867 Phaseolus lunatus 572  
PvLabOv.07G051300.2.p PAC:50242837 Phaseolus vulgaris Labor Ovalle 668  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10666622
            10860730