Protein Domain : IPR006422

Type:  Family Name:  D-erythrose-4-phosphate dehydrogenase
Description:  This entry contains a small clade of dehydrogenases in gamma-proteobacteria which utilise NAD+ to oxidize erythrose-4-phosphate (E4P) to 4-phospho-erythronate, a precursor for the de novo synthesis of pyridoxine via 4-hydroxythreonine and D-1-deoxyxylulose []. This enzyme activity appears to have evolved from glyceraldehyde-3-phosphate dehydrogenase, whose substrate differs only in the lack of one carbon relative to E4P. It is possible that some of the GAPDH enzymes may prove to be bifunctional in certain species. Short Name:  E4P_DH_bac
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0 Child Features

4 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain
IPR020828 Domain Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020829 Domain Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR020830 Active_site Glyceraldehyde 3-phosphate dehydrogenase, active site

2 Cross Referencess

Identifier
TIGR01532
MF_01640

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0048001 IPR006422
GO:0051287 IPR006422
GO:0042823 IPR006422
GO:0055114 IPR006422
GO:0005737 IPR006422

5 Ontology Annotations

GO Term Gene Name
GO:0048001 IPR006422
GO:0051287 IPR006422
GO:0042823 IPR006422
GO:0055114 IPR006422
GO:0005737 IPR006422

1 Parent Features

DB identifier Type Name
IPR020831 Family Glyceraldehyde/Erythrose phosphate dehydrogenase family

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1007393m.p PAC:33607963 Brachypodium distachyon Pangenome 351  
Brdisv1pangenome1007814m.p PAC:33624051 Brachypodium distachyon Pangenome 341  
Brdisv1pangenome1009000m.p PAC:33656070 Brachypodium distachyon Pangenome 341  
Brdisv1BdTR11A1042276m.p PAC:35689364 Brachypodium distachyon BdTR11a 343  
Brdisv1BdTR11A1040480m.p PAC:35688008 Brachypodium distachyon BdTR11a 341  
Brdisv1BdTR11A1040224m.p PAC:35694209 Brachypodium distachyon BdTR11a 341  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7751290