Protein Domain : IPR013461

Type:  Family Name:  ATP-dependent Clp protease ATP-binding subunit ClpA
Description:  Proteins in this entry are related to ClpA () from Escherichia coli. ClpA is an ATP-dependent chaperone and part of the ClpAP protease that participates in regulatory protein degradation and the dissolution and degradation of protein aggregates []. ClpA recognises sequences in specific proteins, which it then unfolds in an ATP-dependent manner and transports into the degradation chamber of the associated ClpP protein [, ]. A small adaptor-like protein, ClpS, modulates the activity of ClpA and is an important regulatory factor for this protein []. It protects ClpA from autodegradation and appears to redirect its activity away from soluble proteins and toward aggregated proteins. Short Name:  ClpA
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0 Child Features

4 Contains

DB identifier Type Name
IPR003959 Domain ATPase, AAA-type, core
IPR019489 Domain Clp ATPase, C-terminal
IPR004176 Domain Clp, N-terminal
IPR018368 Conserved_site ClpA/B, conserved site 1

2 Cross Referencess

Identifier
PTHR11638:SF14
TIGR02639

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0004176 IPR013461

1 Ontology Annotations

GO Term Gene Name
GO:0004176 IPR013461

1 Parent Features

DB identifier Type Name
IPR001270 Family ClpA/B family

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1005566m.p PAC:33622627 Brachypodium distachyon Pangenome 720  
Brdisv1BdTR11A1029410m.p PAC:35678868 Brachypodium distachyon BdTR11a 720  
Brdisv1BdTR11A1043217m.p PAC:35693398 Brachypodium distachyon BdTR11a 894  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12235156
            10485712
            2186030
            11287666