Protein Domain : IPR009675

Type:  Family Name:  TPX2
Description:  This family represents the eukaryotic targeting protein for Xklp2 (TPX2). TPX2 is a microtubule-associated protein that targets a plus end-directed motor (Xklp2) to the minus ends of microtubules in the mitotic spindle. In Xenopus, it has been shown that Xklp2 protein is required for centrosome separation and maintenance of spindle bi-polarity []. It is phosphorylated during mitosis in a microtubule-dependent way []. TPX2 activates Aurora A kinase by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation []. Short Name:  TPX2_fam
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR14326

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0032147 IPR009675
GO:0060236 IPR009675
GO:0005819 IPR009675
GO:0005874 IPR009675

4 Ontology Annotations

GO Term Gene Name
GO:0032147 IPR009675
GO:0060236 IPR009675
GO:0005819 IPR009675
GO:0005874 IPR009675

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
418415 D8S5M3 PAC:15406630 Selaginella moellendorffii 643  
evm.model.supercontig_14.165 PAC:16408664 Carica papaya 522  
evm.model.supercontig_178.6 PAC:16411172 Carica papaya 70  
evm.model.supercontig_29.55 PAC:16416264 Carica papaya 552  
evm.model.supercontig_3.260 PAC:16416547 Carica papaya 494  
evm.model.supercontig_83.73 PAC:16427215 Carica papaya 800  
29983.m003156 B9RVW1 PAC:16814924 Ricinus communis 702  
30147.m014166 B9R9M3 PAC:16820179 Ricinus communis 412  
29630.m000800 B9SJC3 PAC:16804047 Ricinus communis 540  
27914.m000414 B9SR84 PAC:16799485 Ricinus communis 171  
Cucsa.320290.1 PAC:16977328 Cucumis sativus 506  
Cucsa.001380.1 PAC:16950888 Cucumis sativus 35  
Cucsa.157930.1 A0A0A0KVS9 PAC:16965046 Cucumis sativus 513  
Cucsa.031700.1 PAC:16952332 Cucumis sativus 54  
Cucsa.195620.1 PAC:16968207 Cucumis sativus 775  
orange1.1g004245m A0A067DGZ5 PAC:18091002 Citrus sinensis 766  
orange1.1g034806m A0A067DK29 PAC:18122737 Citrus sinensis 82  
orange1.1g021810m A0A067G2Z8 PAC:18135421 Citrus sinensis 307  
orange1.1g032002m A0A067FGV0 PAC:18127795 Citrus sinensis 149  
orange1.1g031976m A0A067FDE6 PAC:18127794 Citrus sinensis 150  
orange1.1g031124m A0A067FD84 PAC:18127793 Citrus sinensis 165  
orange1.1g042640m A0A067FQA8 PAC:18127738 Citrus sinensis 188  
orange1.1g010100m A0A067FC59 PAC:18120303 Citrus sinensis 518  
orange1.1g009390m A0A067F8Q7 PAC:18120302 Citrus sinensis 535  
orange1.1g010096m A0A067FC59 PAC:18120304 Citrus sinensis 518  
orange1.1g011704m A0A067FKL1 PAC:18120305 Citrus sinensis 479  
AT4G11990.1 Q4V3B0 PAC:19645894 Arabidopsis thaliana 501  
AT4G22860.2 A8MS21 PAC:19647174 Arabidopsis thaliana 501  
AT4G22860.1 Q4V3C5 PAC:19647173 Arabidopsis thaliana 509  
AT5G07170.1 PAC:19673214 Arabidopsis thaliana 394  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8548825
            10871281
            18663142