GO Term : GO:0005874 microtubule GO

Namespace:  cellular_component Obsolete:  false
description  Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0005874 112368 GO
GOAnnotation GO:0005874 112368  
OntologyAnnotation GO:0005874 233509 GO
GOAnnotation GO:0005874 233509  
OntologyAnnotation GO:0005874 233518 GO
GOAnnotation GO:0005874 233518  
GOAnnotation GO:0005874 419896  
OntologyAnnotation GO:0005874 419896 GO
GOAnnotation GO:0005874 420234  
OntologyAnnotation GO:0005874 420234 GO
GOAnnotation GO:0005874 114259  
OntologyAnnotation GO:0005874 114259 GO
GOAnnotation GO:0005874 114265  
OntologyAnnotation GO:0005874 114265 GO
GOAnnotation GO:0005874 233699  
OntologyAnnotation GO:0005874 233699 GO
GOAnnotation GO:0005874 420969  
OntologyAnnotation GO:0005874 420969 GO
GOAnnotation GO:0005874 178975  
OntologyAnnotation GO:0005874 178975 GO
GOAnnotation GO:0005874 230496  
OntologyAnnotation GO:0005874 230496 GO
GOAnnotation GO:0005874 23429  
OntologyAnnotation GO:0005874 23429 GO
GOAnnotation GO:0005874 234301  
OntologyAnnotation GO:0005874 234301 GO
OntologyAnnotation GO:0005874 119313 GO
GOAnnotation GO:0005874 119313  
GOAnnotation GO:0005874 125554  
OntologyAnnotation GO:0005874 125554 GO

17 Parents

Identifier Name Description
GO:0005874 microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005856 cytoskeleton Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044422 organelle part Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
GO:0044446 intracellular organelle part A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
GO:0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0044430 cytoskeletal part Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
GO:0015630 microtubule cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

59 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005874 GO:0000235
is_a GO:0005874 GO:0005827
is_a GO:0005874 GO:0005828
is_a GO:0043234 GO:0005874
part of GO:0015630 GO:0005874
is_a GO:0044430 GO:0005874
part of GO:0005622 GO:0005874
part of GO:0005623 GO:0005874
part of GO:0005856 GO:0005874
is_a GO:0044422 GO:0005874
is_a GO:0044446 GO:0005874
is_a GO:0044424 GO:0005874
is_a GO:0032991 GO:0005874
part of GO:0043226 GO:0005874
part of GO:0043232 GO:0005874
is_a GO:0005575 GO:0005874
part of GO:0044464 GO:0005874
is_a GO:0044464 GO:0005874
part of GO:0005575 GO:0005874
part of GO:0044424 GO:0005874
part of GO:0043229 GO:0005874
part of GO:0043228 GO:0005874
is_a GO:0005874 GO:0005876
is_a GO:0005874 GO:0005876
is_a GO:0005874 GO:0005879
is_a GO:0005874 GO:0005879
is_a GO:0005874 GO:0005880
is_a GO:0005874 GO:0005880
is_a GO:0005874 GO:0005881
is_a GO:0005874 GO:0005881

3 Synonyms

Name Type
microtubulus synonym
microtubuli synonym
neurotubule synonym