Protein Domain : IPR016454

Type:  Family Name:  Cysteine desulfurase
Description:  This group represents a cysteine desulfurase, NifS type. NifS-like proteins are homodimeric and belong to the alpha-family of pyridoxal-5'-phoshate dependent enzymes [] which catalyse the reaction: L-cysteine + (enzyme)-cysteine = L-alanine + (enzyme)-S-sulphanylcysteine Cysteine desulfurase proteins play a central role in the delivery of sulphur to a variety of metabolic pathways []. It is involved in the biosynthesis of iron-sulphur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) []. They are present in all organisms (except viruses). In eukaryotes these enzymes occur in mitochondria since this is the primary site for Fe-S cluster assembly []. Short Name:  Cysteine_dSase
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5 Child Features

DB identifier Type Name
IPR010970 Family Cysteine desulfurase, SufS
IPR010240 Family Cysteine desulfurase IscS
IPR017644 Family Cysteine desulfurase DndA
IPR017772 Family Cysteine desulfurase NifS, bacterial/archaeal
IPR017773 Family Cysteine desulfurase NifS, proteobacteria

2 Contains

DB identifier Type Name
IPR015421 Domain Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR020578 Binding_site Aminotransferase class-V, pyridoxal-phosphate binding site

1 Cross References

Identifier
PIRSF005572

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

417 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
105841 D8S0K7 PAC:15417944 Selaginella moellendorffii 409  
evm.model.supercontig_129.49 PAC:16407552 Carica papaya 455  
28830.m000224 B9T178 PAC:16801755 Ricinus communis 453  
Cucsa.103520.1 PAC:16959052 Cucumis sativus 458  
orange1.1g040741m A0A067GTN7 PAC:18124784 Citrus sinensis 457  
AT5G65720.1 O49543 PAC:19671222 Arabidopsis thaliana 453  
Thhalv10004176m V4KJ97 PAC:20199102 Eutrema salsugineum 459  
Ciclev10025572m V4UJ66 PAC:20801567 Citrus clementina 457  
Lus10011590 PAC:23142779 Linum usitatissimum 465  
Lus10019252 PAC:23141314 Linum usitatissimum 460  
Potri.007G000600.1 B9HG88 PAC:27014772 Populus trichocarpa 452  
Gorai.008G087200.1 PAC:26815604 Gossypium raimondii 435  
Gorai.009G268800.1 A0A0D2TW08 PAC:26761885 Gossypium raimondii 450  
14927 I0Z0B3 PAC:27391094 Coccomyxa subellipsoidea C-169 413  
21333 C1N3B7 PAC:27348943 Micromonas pusilla CCMP1545 406  
15684 C1MNN5 PAC:27346980 Micromonas pusilla CCMP1545 446  
108046 C1E3B7 PAC:27400423 Micromonas sp RCC299 409  
45194 A4RUB0 PAC:27413195 Ostreococcus lucimarinus 395  
16873 A4S300 PAC:27413736 Ostreococcus lucimarinus 405  
Thecc1EG000875t1 A0A061DIS8 PAC:27435192 Theobroma cacao 450  
Araha.11756s0259.1.p PAC:28856571 Arabidopsis halleri 404  
Araha.45956s0001.1.p PAC:28852660 Arabidopsis halleri 395  
Cagra.0917s0013.1.p PAC:28909353 Capsella grandiflora 457  
Glyma.11G044600.1.p I1LH30 PAC:30530568 Glycine max 457  
Glyma.01G197100.1.p I1J9H6 PAC:30543492 Glycine max 457  
Glyma.01G197100.2.p I1J9H6 PAC:30543491 Glycine max 457  
Brara.I00830.1.p A0A397XRZ7 PAC:30641202 Brassica rapa FPsc 457  
Bostr.0568s0213.1.p PAC:30669628 Boechera stricta 460  
Cre02.g146250.t1.2 A0A2K3E3W0 PAC:30784892 Chlamydomonas reinhardtii 464  
Medtr5g014820.1 G7K149 PAC:31089495 Medicago truncatula 454  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12382038
            10715213
            12860127
            12033984