| Type: | Domain | Name: | Cold shock protein |
| Description: | A conserved domain of about 70 amino acids has been found in prokaryotic and eukaryotic single-strand nucleic-acid binding proteins [, , , , ]. This domain, which is known as the 'cold-shock domain' (CSD) is present in the proteins listed below.Escherichia coliprotein CS7.4 (gene cspA) which is induced in response to low temperature (cold-shock protein) and which binds to and stimulates the transcription of the CCAAT-containing promoters of the HN-S protein and of gyrA.Transcription termination factor Rho, a prokaryotic protein which facilitates transcription termination.Mammalian Y box binding protein 1 (YB1). A protein that binds to the CCAAT-containing Y box of mammalian HLA class II genes.Xenopus Y box binding proteins -1 and -2 (Y1 and Y2). Proteins that bind to the CCAAT-containing Y box of Xenopus hsp70 genes.Xenopus B box binding protein (YB3). YB3 binds the B box promoter element of genes transcribed by RNA polymerase III.Enhancer factor I subunit A (EFI-A) (dbpB). A protein that also bind to CCAAT-motif in various gene promoters.DbpA, a human DNA-binding protein of unknown specificity.Bacillus subtiliscold-shock proteins cspB and cspC.Streptomyces clavuligerusprotein SC 7.0.E. coli proteins cspB, cspC, cspD, cspE and cspF.Unr, a mammalian gene encoded upstream of the N-ras gene. Unr contains nine repeats that are similar to the CSD domain. The function of Unr is not yet known but it could be a multivalent DNA-binding protein.PPPin, a mammalian brain-specific protein that binds to histone mRNA and which is thought to play a role in the regulation of brain development. | Short Name: | Cold_shock_prot |
