Protein Domain : IPR027674

Type:  Family Name:  Exostosin 3/Exostosin-like 3
Description:  There are five identiied human EXT family proteins (EXT1, EXT2, EXTL1, EXTL2 and EXTL3), which are members of the hereditary multiple exostoses family of tumor suppressors []. Exostosin-3 (EXT3) from Drosophila melanogaster and exostosin-like 3 (EXTL3) are N-acetylglucosamine transferases involved in heparan sulfate biosynthesis [, ]. This entry also include Caenorhabditis elegans exostosin-2 (also known as rib-2). In Caenorhabditis elegans, only two proteins, EXT1 (rib-1) and EXT2 (rib-2), homologous to the mammalian EXT genes have been identified []. Short Name:  EXO3/EXOL3
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR11062:SF57

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0015012 IPR027674
GO:0016021 IPR027674

2 Ontology Annotations

GO Term Gene Name
GO:0015012 IPR027674
GO:0016021 IPR027674

1 Parent Features

DB identifier Type Name
IPR004263 Family Exostosin-like

82 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
23945 D8RPK2 PAC:15419407 Selaginella moellendorffii 305  
Sphfalx0118s0015.1.p PAC:32614887 Sphagnum fallax 341  
Sphfalx0118s0016.1.p PAC:32614888 Sphagnum fallax 374  
Sphfalx0070s0034.1.p PAC:32606646 Sphagnum fallax 612  
Sphfalx0092s0046.1.p PAC:32610345 Sphagnum fallax 327  
Sphfalx0028s0143.1.p PAC:32627168 Sphagnum fallax 390  
Pp3c14_23920V3.1.p A9SDZ4 PAC:32960968 Physcomitrium patens 429  
Pp3c14_23920V3.2.p A9SDZ4 PAC:32960969 Physcomitrium patens 429  
Pp3c17_22930V3.2.p A9SDP0 PAC:32906127 Physcomitrium patens 438  
Pp3c17_22930V3.3.p A9SDP0 PAC:32906128 Physcomitrium patens 438  
Pp3c17_22930V3.4.p A9SDP0 PAC:32906129 Physcomitrium patens 438  
Pp3c17_22930V3.1.p A9SDP0 PAC:32906126 Physcomitrium patens 438  
Pp3c1_41910V3.2.p A9SS41 PAC:32969660 Physcomitrium patens 433  
Pp3c1_41910V3.1.p A9SS41 PAC:32969659 Physcomitrium patens 433  
Pp3c2_820V3.2.p PAC:32933146 Physcomitrium patens 125  
Pp3c3_23480V3.2.p A0A2K1KVT2 PAC:32941046 Physcomitrium patens 522  
Pp3c3_23480V3.1.p A0A2K1KVT2 PAC:32941045 Physcomitrium patens 522  
Pp3c3_22580V3.1.p A0A2K1KVJ9 PAC:32942118 Physcomitrium patens 434  
Pp3c3_22580V3.7.p A0A2K1KVJ9 PAC:32942124 Physcomitrium patens 434  
Pp3c3_22580V3.6.p A0A2K1KVJ9 PAC:32942123 Physcomitrium patens 434  
Pp3c3_22580V3.4.p A0A2K1KVJ9 PAC:32942121 Physcomitrium patens 434  
Pp3c3_22580V3.3.p A0A2K1KVJ9 PAC:32942120 Physcomitrium patens 434  
Pp3c3_22580V3.11.p A0A2K1KVJ9 PAC:32942128 Physcomitrium patens 434  
Pp3c3_22580V3.12.p A0A2K1KVJ9 PAC:32942129 Physcomitrium patens 434  
Pp3c3_22580V3.5.p A0A2K1KVJ9 PAC:32942122 Physcomitrium patens 434  
Pp3c3_22580V3.8.p A0A2K1KVJ9 PAC:32942125 Physcomitrium patens 434  
Pp3c3_22580V3.10.p A0A2K1KVJ9 PAC:32942127 Physcomitrium patens 434  
Pp3c3_22580V3.2.p A0A2K1KVJ9 PAC:32942119 Physcomitrium patens 434  
Pp3c3_22580V3.9.p A0A2K1KVJ9 PAC:32942126 Physcomitrium patens 434  
Pp3c3_22700V3.1.p A0A2K1KVP6 PAC:32942785 Physcomitrium patens 374  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17237233
            9479495
            11832488