GO Term : GO:0015012 heparan sulfate proteoglycan biosynthetic process GO

Namespace:  biological_process Obsolete:  false
description  The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0015012 81258  
OntologyAnnotation GO:0015012 81258 GO
GOAnnotation GO:0015012 420395  
OntologyAnnotation GO:0015012 420395 GO
GOAnnotation GO:0015012 139351  
OntologyAnnotation GO:0015012 139351 GO
GOAnnotation GO:0015012 403218  
OntologyAnnotation GO:0015012 403218 GO
OntologyAnnotation GO:0015012 133103 GO
GOAnnotation GO:0015012 133103  
OntologyAnnotation GO:0015012 23945 GO
GOAnnotation GO:0015012 23945  
OntologyAnnotation GO:0015012 evm.model.supercontig_128.65 GO
GOAnnotation GO:0015012 evm.TU.supercontig_128.65  
GOAnnotation GO:0015012 evm.TU.supercontig_19.204  
OntologyAnnotation GO:0015012 evm.model.supercontig_19.204 GO
OntologyAnnotation GO:0015012 evm.model.supercontig_4.178 GO
GOAnnotation GO:0015012 evm.TU.supercontig_4.178  
OntologyAnnotation GO:0015012 evm.model.supercontig_488.3 GO
GOAnnotation GO:0015012 evm.TU.supercontig_488.3  
OntologyAnnotation GO:0015012 27916.m000159 GO
GOAnnotation GO:0015012 27916.t000008  
OntologyAnnotation GO:0015012 29589.m001291 GO
GOAnnotation GO:0015012 29589.t000070  
OntologyAnnotation GO:0015012 29669.m000810 GO
GOAnnotation GO:0015012 29669.t000019  
GOAnnotation GO:0015012 30147.t000420  
OntologyAnnotation GO:0015012 30147.m014149 GO
GOAnnotation GO:0015012 Cucsa.308870  
OntologyAnnotation GO:0015012 Cucsa.308870.1 GO

31 Parents

Identifier Name Description
GO:0015012 heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006082 organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0006790 sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0044711 single-organism biosynthetic process A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:0009100 glycoprotein metabolic process The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0009101 glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0034645 cellular macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GO:0043436 oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
GO:0044281 small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0044272 sulfur compound biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0006029 proteoglycan metabolic process The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:0030166 proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.

40 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:0015012 GO:0010908
regulates GO:0015012 GO:0010908
positively regulates GO:0015012 GO:0010909
positively regulates GO:0015012 GO:0010909
regulates GO:0015012 GO:0010909
positively regulates GO:0015012 GO:0010910
regulates GO:0015012 GO:0010910
is_a GO:0030201 GO:0015012
is_a GO:0044272 GO:0015012
is_a GO:0030166 GO:0015012
is_a GO:0044711 GO:0015012
is_a GO:0009987 GO:0015012
is_a GO:1901135 GO:0015012
is_a GO:0006790 GO:0015012
is_a GO:0044237 GO:0015012
is_a GO:0009100 GO:0015012
is_a GO:0044710 GO:0015012
is_a GO:0044699 GO:0015012
is_a GO:0009101 GO:0015012
is_a GO:1901576 GO:0015012
is_a GO:1901137 GO:0015012
is_a GO:0044238 GO:0015012
is_a GO:0006082 GO:0015012
is_a GO:0034645 GO:0015012
is_a GO:0006029 GO:0015012
is_a GO:0043170 GO:0015012
is_a GO:0044281 GO:0015012
is_a GO:0044260 GO:0015012
is_a GO:0009059 GO:0015012
is_a GO:0009058 GO:0015012

7 Synonyms

Name Type
heparan sulfate proteoglycan anabolism synonym
heparan sulfate proteoglycan formation synonym
heparan sulfate proteoglycan biosynthesis synonym
heparan sulphate proteoglycan biosynthesis synonym
heparan sulfate proteoglycan synthesis synonym
heparin proteoglycan biosynthetic process synonym
heparan sulphate proteoglycan biosynthetic process synonym