Protein Domain : IPR015269

Type:  Domain Name:  Uncharacterised domain UPF0029, Impact, C-terminal
Description:  Members of this entry are a set of functionally uncharacterised hypothetical bacterial proteins. They adopt a ferredoxin-like fold, with a beta-alpha-beta-beta-alpha-beta arrangement []. This entry contains the protein Impact, which is a translational regulator that ensures constant high levels of translation under amino acid starvation. It acts by interacting with Gcn1/Gcn1L1, thereby preventing activation of Gcn2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. It is evolutionary conserved from eukaryotes to archaea []. Short Name:  UPF0029_Impact_C

0 Child Features

0 Contains

1 Cross References

Identifier
PF09186

1 Found In

DB identifier Type Name
IPR015796 Family Impact family, bacterial/archaeal

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR009022 Domain Elongation factor G, III-V domain

21 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
404562 D8QVQ8 PAC:15411072 Selaginella moellendorffii 155  
109131 C1EDW3 PAC:27404970 Micromonas sp RCC299 253  
37283 A4RVU2 PAC:27415580 Ostreococcus lucimarinus 239  
Cre10.g448800.t1.1 A0A2K3DB12 PAC:30790507 Chlamydomonas reinhardtii 267  
Dusal.0693s00005.1.p PAC:33196175 Dunaliella salina 253  
Brdisv1Uni21041240m.p PAC:33293744 Brachypodium distachyon Uni2 164  
Brdisv1pangenome1006944m.p PAC:33623590 Brachypodium distachyon Pangenome 355  
Brdisv1ABR6_r1045238m.p PAC:33703079 Brachypodium distachyon ABR6 78  
Brdisv1ABR21043863m.p PAC:33749669 Brachypodium distachyon ABR2 107  
Brdisv1Gaz-81021036m.p PAC:33834214 Brachypodium distachyon Gaz-8 107  
Brdisv1Bd29-11036537m.p PAC:34150773 Brachypodium distachyon Bd29-1 107  
Brdisv1Bd29-11036536m.p PAC:34148723 Brachypodium distachyon Bd29-1 72  
Brdisv1Mon31018174m.p PAC:34315989 Brachypodium distachyon Mon3 107  
Brdisv1RON21044823m.p PAC:34776510 Brachypodium distachyon Ron2 162  
Brdisv1ABR41043408m.p PAC:34963069 Brachypodium distachyon ABR4 164  
Brdisv1ABR41046316m.p PAC:34965958 Brachypodium distachyon ABR4 107  
Brdisv1Sig21017304m.p PAC:35264250 Brachypodium distachyon Sig2 107  
Brdisv1BdTR11A1041747m.p PAC:35694925 Brachypodium distachyon BdTR11a 221  
Cz10g07170.t1 PAC:38243879 Chromochloris zofingiensis 212  
Bobra.0363s0021.1.p PAC:40718265 Botryococcus braunii 255  
Vocar.0070s0010.1.p PAC:32895829 Volvox carteri 305  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11116084
            15103642