| Type: | Family | Name: | Graves disease carrier protein |
| Description: | A variety of substrate carrier proteins that are involved in energy transfer are found in the inner mitochondrial membrane [, , , ]. Such proteins include:ADP,ATP carrier protein (ADP/ATP translocase); 2-oxoglutarate/malate carrier protein; phosphate carrier protein; tricarboxylate transport protein (orcitrate transport protein); Graves disease carrier protein; yeast mitochondrial proteins MRS3 and MRS4; yeast mitochondrial FAD carrier protein;and many others.Graves disease carrier protein (GDC) is a protein of as yet uncharacterised function that belongs to the mitochondrial metabolite carrier family(which includes the ADP/ATP translocator, the phosphate carrier and the hydrogen ion uncoupling protein) [, ]. The protein is recognised by IgGfrom patients with active Graves disease.GDC is an integral membrane protein thought to reside in the inner mitochondrial membrane. The predicted amino acid sequence of 348 residuescomprises three similar domains. | Short Name: | Graves_DC |
