Protein Domain : IPR003918

Type:  Family Name:  NADH:ubiquinone oxidoreductase
Description:  NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry contains members of the subunit families 4, 2 and 5 from complex I. Short Name:  NADH_UbQ_OxRdtase
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2 Child Features

DB identifier Type Name
IPR010227 Family NADH-quinone oxidoreductase, chain M/4
IPR004775 Family Na(+)/H(+) antiporter subunit D1

1 Contains

DB identifier Type Name
IPR001750 Domain NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit

1 Cross References

Identifier
PR01437

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008137 IPR003918
GO:0042773 IPR003918
GO:0055114 IPR003918

3 Ontology Annotations

GO Term Gene Name
GO:0008137 IPR003918
GO:0042773 IPR003918
GO:0055114 IPR003918

0 Parent Features

347 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
137786 D8TE48 PAC:15422313 Selaginella moellendorffii 524  
139131 PAC:15423449 Selaginella moellendorffii 531  
42076.m000069 B9T8W8 PAC:16827492 Ricinus communis 366  
Cucsa.245810.1 PAC:16971391 Cucumis sativus 249  
ATMG00580.1 G1C2U9 PAC:19643646 Arabidopsis thaliana 495  
ATCG01050.1 PAC:19637969 Arabidopsis thaliana 506  
Ciclev10027631m PAC:20814918 Citrus clementina 194  
Ciclev10010880m V4TB62 PAC:20796223 Citrus clementina 243  
Ciclev10013969m PAC:20785359 Citrus clementina 148  
Ciclev10013974m PAC:20799305 Citrus clementina 220  
Ciclev10027650m PAC:20819343 Citrus clementina 244  
Araha.11756s0376.1.p PAC:28856497 Arabidopsis halleri 505  
Araha.7988s0003.1.p PAC:28841588 Arabidopsis halleri 243  
Cagra.5120s0013.1.p PAC:28904239 Capsella grandiflora 502  
Glyma.U008600.1.p A0A0R0C7N6 PAC:30500052 Glycine max 245  
Bostr.12863s0002.1.p PAC:30674417 Boechera stricta 451  
Bostr.14452s0002.1.p PAC:30664611 Boechera stricta 254  
Medtr2g103350.1 G7IUT1 PAC:31066822 Medicago truncatula 137  
Medtr3g073110.1 G7J3M4 PAC:31057048 Medicago truncatula 176  
Medtr4g006120.1 G7JVM1 PAC:31108534 Medicago truncatula 573  
Medtr4g050950.1 G7JFZ4 PAC:31115242 Medicago truncatula 498  
Medtr4g086110.1 G7JL83 PAC:31109386 Medicago truncatula 126  
Medtr4g080900.1 PAC:31106293 Medicago truncatula 199  
Medtr5g032430.1 G7JXQ2 PAC:31085090 Medicago truncatula 112  
Medtr5g089040.1 G7KCU5 PAC:31090499 Medicago truncatula 144  
Medtr7g086590.1 G7L1J2 PAC:31082620 Medicago truncatula 135  
Medtr7g021720.1 G7KTU3 PAC:31082976 Medicago truncatula 587  
Medtr7g075220.1 G7L0B6 PAC:31077339 Medicago truncatula 994  
Medtr7g112630.1 G7KXI2 PAC:31081565 Medicago truncatula 95  
Medtr0082s0060.1 A0A072THH4 PAC:31076829 Medicago truncatula 346  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1470679
            10940377
            18394423