1 Contains
| DB identifier | Type | Name |
|---|---|---|
| IPR019594 | Domain | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
| Type: | Domain | Name: | Ionotropic glutamate receptor |
| Description: | Ionotropic glutamate receptors (iGluRs) are a highly conserved family of ligand-gated ion channels present in animals, plants, and bacteria, which are best characterised for their roles in synaptic communication in vertebrate nervous systems []. A variant subfamily of iGluRs, the Ionotropic Receptors (IRs), consist of non-glutamate-binding chemosensory receptors first identified inDrosophila melanogaster. They function in detecting odors and tastants [].There are three classes of ionotropic glutamate receptors (iGluRs), namely NMDA (N-methyl-D-aspartate), AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionic acid) and kainate receptors. They are believed to play critical roles in synaptic plasticity. At many synapses in the brain, transient activation of NMDA receptors leads to a persistent modification in the strength of synaptic transmission mediated by AMPA receptors and kainate receptors can act as the induction trigger for long-term changes in synaptic transmission []. | Short Name: | Iontro_rcpt |
| DB identifier | Type | Name |
|---|---|---|
| IPR019594 | Domain | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
