|
GO:0006810
|
transport
|
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. |
|
GO:0055085
|
transmembrane transport
|
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other |
|
GO:0005488
|
binding
|
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
|
GO:0007165
|
signal transduction
|
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
|
GO:0022857
|
transmembrane transporter activity
|
Enables the transfer of a substance from one side of a membrane to the other. |
|
GO:0005215
|
transporter activity
|
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. |
|
GO:0022891
|
substrate-specific transmembrane transporter activity
|
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other. |
|
GO:0005216
|
ion channel activity
|
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). |
|
GO:0006811
|
ion transport
|
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
|
GO:0004871
|
signal transducer activity
|
Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
|
GO:0034220
|
ion transmembrane transport
|
A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
|
GO:0015075
|
ion transmembrane transporter activity
|
Enables the transfer of an ion from one side of a membrane to the other. |
|
GO:0016597
|
amino acid binding
|
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents. |
|
GO:0004888
|
transmembrane signaling receptor activity
|
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
|
GO:0007166
|
cell surface receptor signaling pathway
|
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
|
GO:0004970
|
ionotropic glutamate receptor activity
|
Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. |
|
GO:0015267
|
channel activity
|
Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. |
|
GO:0004872
|
receptor activity
|
Combining with an extracellular or intracellular messenger to initiate a change in cell activity. |
|
GO:0051716
|
cellular response to stimulus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
|
GO:0036094
|
small molecule binding
|
Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule. |
|
GO:0005230
|
extracellular ligand-gated ion channel activity
|
Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. |
|
GO:0007154
|
cell communication
|
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
|
GO:0009987
|
cellular process
|
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
|
GO:0043167
|
ion binding
|
Interacting selectively and non-covalently with ions, charged atoms or groups of atoms. |
|
GO:0044763
|
single-organism cellular process
|
Any process that is carried out at the cellular level, occurring within a single organism. |
|
GO:0044699
|
single-organism process
|
A biological process that involves only one organism. |
|
GO:0051179
|
localization
|
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location. |
|
GO:1902578
|
single-organism localization
|
A localization which involves only one organism. |
|
GO:0008150
|
biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
|
GO:0022892
|
substrate-specific transporter activity
|
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. |
