Protein Domain : IPR013022

Type:  Domain Name:  Xylose isomerase-like, TIM barrel domain
Description:  This entry represents a structural motif with a beta/alpha TIM barrel found in several proteins families:Endonuclease IV (), an AP (apurinic/apyrimidinic) endonuclease that primes DNA repair synthesis by cleaving the DNA backbone 5' of AP sites [].L-rhamnose isomerase (), a tetramer of four TIM barrels that catalyses the isomerisation between aldoses and ketoses, such as between L-rhamnose and L-rhamnulose [].Xylose isomerase (), which catalyses the first reaction in the catabolism of D-xylose by converting D-xylose to D-xylulose [].Mannonate dehydratase UxuA, which along with mannonate oxidoreductase converts D-fructuronate to 2-keto-3-deoxy-D-gluconate [].These proteins share similar, but not identical, metal-binding sites. In addition, xylose isomerase and L-rhamnose isomerase each have additional alpha-helical domains involved in tetramer formation. Short Name:  Xyl_isomerase-like_TIM-brl
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0 Child Features

2 Contains

DB identifier Type Name
IPR018246 Binding_site AP endonuclease 2, zinc binding site
IPR011418 Domain AP endonuclease, family 2, C-terminal

3 Cross Referencess

Identifier
PF01261
G3DSA:3.20.20.150
SSF51658

10 Found Ins

DB identifier Type Name
IPR013452 Family Xylose isomerase, bacterial-type
IPR004601 Family UV-endonuclease UvdE
IPR017643 Family Hydroxypyruvate isomerase
IPR004560 Family L-ribulose-5-phosphate 3-epimerase
IPR004628 Family Mannonate dehydratase
IPR014621 Family Uncharacterised conserved protein UCP036778, sugar epimerase-type
IPR009308 Family Rhamnose isomerase
IPR013453 Family Xylose isomerase, actinobacteria
IPR013451 Family L-rhamnose catabolism isomerase
IPR013457 Family Rhamnose isomerase-related

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
27859 D8TAQ7 PAC:15407941 Selaginella moellendorffii 105  
431017 D8TB94 PAC:15419876 Selaginella moellendorffii 584  
411648 D8RIL1 PAC:15410183 Selaginella moellendorffii 158  
413362 D8RP78 PAC:15413822 Selaginella moellendorffii 337  
161472 D8T6H4 PAC:15401804 Selaginella moellendorffii 478  
evm.TU.contig_41395.1 PAC:16431605 Carica papaya 112  
evm.model.supercontig_22.84 PAC:16413927 Carica papaya 113  
evm.model.supercontig_75.2 PAC:16425856 Carica papaya 476  
evm.model.supercontig_755.3 PAC:16425961 Carica papaya 271  
evm.model.supercontig_95.75 PAC:16428919 Carica papaya 479  
29739.m003710 B9RR58 PAC:16807489 Ricinus communis 1233  
29848.m004536 B9RNV5 PAC:16811192 Ricinus communis 617  
30138.m003990 B9RLQ3 PAC:16819356 Ricinus communis 147  
30959.m000027 B9TGB8 PAC:16824729 Ricinus communis 248  
31973.m000023 B9TGN9 PAC:16825264 Ricinus communis 51  
33907.m000029 B9TIK6 PAC:16826031 Ricinus communis 193  
35848.m000028 B9TEG1 PAC:16826751 Ricinus communis 262  
29132.m000043 PAC:16802339 Ricinus communis 379  
28570.m000028 B9TBV4 PAC:16801125 Ricinus communis 625  
27766.m000154 B9T2E0 PAC:16799138 Ricinus communis 477  
27380.m000067 B9TAW3 PAC:16798174 Ricinus communis 283  
Cucsa.089630.7 A0A0A0LK73 PAC:16957183 Cucumis sativus 476  
Cucsa.089630.16 PAC:16957175 Cucumis sativus 468  
Cucsa.089630.17 PAC:16957176 Cucumis sativus 405  
Cucsa.089630.18 PAC:16957177 Cucumis sativus 398  
Cucsa.089630.11 A0A0A0LK73 PAC:16957170 Cucumis sativus 476  
Cucsa.089630.12 A0A0A0LK73 PAC:16957171 Cucumis sativus 476  
Cucsa.089630.1 A0A0A0LK73 PAC:16957168 Cucumis sativus 476  
Cucsa.110070.1 A0A0A0LP06 PAC:16959981 Cucumis sativus 361  
Cucsa.179440.1 PAC:16967192 Cucumis sativus 352  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10458614
            17141803
            16673077
            7007313