Protein Domain : IPR004560

Type:  Family Name:  L-ribulose-5-phosphate 3-epimerase
Description:  L-ribulose-5-phosphate 3-epimerase () are suspected to be involved in isomerisation of L-xylulose-5-phosphate to L-ribulose-5-phosphate. UlaE in E. coli contains a TIM barrel and forms dimers [].The ulaABCDEF operon encodes an L-ascorbate phosphotransferase transport system (UlaABC, formerly designated SgaTBA)responsible for the uptake and phosphorylation of L-ascorbate. The ulaDEF genes encode three enzymes that catalyze the anaerobic conversion of the phosphorylated, hydrolytic product of L-ascorbate, 3-keto-L-gulonate-6-phosphate, to D-xylulose-5-phosphate, which is subsequently metabolized by the pentose phosphate pathway. UlaD catalyzes a beta-keto acid decarboxylation reaction to produce L-xylulose-5-phosphate, which undergoes successive epimerization reactions with UlaE (L-xylulose-5-phosphate 3-epimerase) and UlaF (L-ribulose-5-phosphate 4-epimerase), yielding D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway. Short Name:  L-Ru-5P_3-Epase

1 Child Features

DB identifier Type Name
IPR023492 Family L-ribulose-5-phosphate 3-epimerase, Enterobacteriaceae

1 Contains

DB identifier Type Name
IPR013022 Domain Xylose isomerase-like, TIM barrel domain

1 Cross References

Identifier
TIGR00542

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0016861 IPR004560
GO:0005975 IPR004560

2 Ontology Annotations

GO Term Gene Name
GO:0016861 IPR004560
GO:0005975 IPR004560

0 Parent Features

0 Proteins

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18849419