| Type: | Domain | Name: | LPXTG cell wall anchor domain |
| Description: | This LPXTG motif-containing region is found at the C terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Proteins that do not lie at the C terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif []. | Short Name: | LPXTG_anchor |
| DB identifier | Type | Name |
|---|---|---|
| IPR019929 | Family | Iron-regulated surface determinant protein IsdB |
| IPR019930 | Family | Haptoglobin-binding haem uptake protein HarA |
| IPR011838 | Domain | Pullulanase, extracellular |
| IPR022440 | Family | Conserved hypothetical protein CHP03788 |
| IPR014579 | Family | Predicted 5'-nucleotidase, SA0022 type |
