1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR019950 | Domain | Surface protein from Gram-positive cocci, anchor region |
| Type: | Domain | Name: | Gram-positive anchor |
| Description: | Viruses, parasites and bacteria are covered in protein and sugar molecules that help them gain entry into a host by counteracting the host's defences. One such molecule is the M protein produced by certain streptococcal bacteria. M proteins embody a motif that is now known to be shared by many Gram-positive bacterial surface proteins. The motif includes a conserved hexapeptide, which precedes a hydrophobic C-terminal membrane anchor, which itself precedes a cluster of basic residues [, ].This structure is represented in the following schematic representation:+--------------------------------------------+-+--------+-+ | Variable length extracellular domain |H| Anchor |B|+--------------------------------------------+-+--------+-+ 'H': conserved hexapeptide.'B': cluster of basic residues. It has been proposed that this hexapeptide sequence is responsible for a post-translational modification necessary for the proper anchoring of the proteins which bear it, to the cell wall. | Short Name: | Gram-positive_anchor |
| DB identifier | Type | Name |
|---|---|---|
| IPR019950 | Domain | Surface protein from Gram-positive cocci, anchor region |
