| Type: | Domain | Name: | Six-bladed beta-propeller, TolB-like |
| Description: | This entry represents a six-bladed beta-propeller domain consisting of six 4-stranded beta-sheet motifs. This domain can be found in TolB proteins (C-terminal), in soluble quinoprotein glucose dehydrogenase, in calcium-dependent phosphotriesterases, in the low density lipoprotein (LDL) receptor YWTD domain, in nidogen, and in serine/threonine-protein kinase (PknD) NHL repeat domain.TolB is a periplasmic protein from Escherichia colithat is part of the Tol-dependent translocation system involving group A and E colicins that is used to penetrate and kill cells [, ]. TolB has two domains, an alpha-helical N-terminal domain () that shares structural similarity with the C-terminal domain of transfer RNA ligases, and a beta-propeller C-terminal domain that shares structural similarity with numerous members of the prolyl oligopeptidase family and, to a lesser extent, to class B metallo-beta-lactamases (although its does not necessarily occur at the C-terminal in these proteins) []. The C-terminal domain of TolB may mediate protein-protein interactions with colicins. | Short Name: | 6-blade_b-propeller_TolB-like |
| DB identifier | Type | Name |
|---|---|---|
| IPR004141 | Family | Strictosidine synthase |
| IPR000720 | Family | Peptidyl-glycine alpha-amidating monooxygenase |
| IPR002640 | Family | Arylesterase |
| IPR016317 | Family | Pro-epidermal growth factor |
| IPR014167 | Family | Tol-Pal system beta propeller repeat-containing protein, TolB |
| IPR017049 | Family | Low density lipoprotein receptor-related protein, 5/6 |
| IPR008363 | Family | Paraoxonase1 |
| IPR008364 | Family | Paraoxonase2 |
| IPR017549 | Domain | Acanthamoeba polyphaga mimivirus, L690 |
