Type: | Family | Name: | Serine incorporator/TMS membrane protein |
Description: | The serine incorporator/TMS membrane protein (TDE1/TMS) family include SERC1-5 from mammals and membrane protein Tms1 from budding yeasts. Members in this family contain eleven transmembrane helices. SERC1-5 function in incorporating serine into membranes and facilitating the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids []. Serinc3 (also known as TDE1) is overexpressed in tumours []. The function of Tms1 is not clear. | Short Name: | TDE1/TMS |