Protein Domain : IPR029555

Type:  Family Name:  Serine incorporator 5
Description:  Serine incorporator (Serinc) 1-5 constitute a family of carrier proteins that incorporate serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Serinc family members contain 11 transmembrane domains []. In the rat brain, expression of Serinc1 and Serinc2 mRNA is up-regulated by induced seizures, whereas Seric5 is down-regulated, indicating a novel mechanism linking neural activity and lipid biosynthesis.This entry represents Serinc5 (also known as Tpo1). It may play a role in myelin formation []. Short Name:  Serinc5
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10383:SF16

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0015194 IPR029555
GO:0006658 IPR029555
GO:0006665 IPR029555
GO:0015825 IPR029555
GO:0042552 IPR029555

5 Ontology Annotations

GO Term Gene Name
GO:0015194 IPR029555
GO:0006658 IPR029555
GO:0006665 IPR029555
GO:0015825 IPR029555
GO:0042552 IPR029555

1 Parent Features

DB identifier Type Name
IPR005016 Family Serine incorporator/TMS membrane protein

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16120614
            16405874