Protein Domain : IPR001736

Type:  Domain Name:  Phospholipase D/Transphosphatidylase
Description:  Phosphatidylcholine-hydrolysing phospholipase D (PLD) isoforms are activated by ADP-ribosylation factors (ARFs). PLD produces phosphatidic acid from phosphatidylcholine, which may be essential for the formation of certain types of transport vesicles or may be constitutive vesicular transport to signal transduction pathways. PC-hydrolysing PLD is a homologue of cardiolipin synthase, phosphatidylserine synthase, bacterial PLDs, and viral proteins. Each of these appears to possess a domain duplication which is apparent by the presence of two motifs containing well-conserved histidine, lysine, and/or asparagine residues which may contribute to the active site aspartic acid. An Escherichia coliendonuclease (nuc) and similar proteins appear to be PLD homologues but possess only one of these motifs [, , , ]. Short Name:  PLipase_D/transphosphatidylase
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0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF00614
PS50035
SM00155

5 Found Ins

DB identifier Type Name
IPR011402 Family Phospholipase D, plant
IPR015679 Family Phospholipase D family
IPR016555 Family Phospholipase D1/D2
IPR016270 Family Phospholipase D, phosphatidylserine synthase type
IPR016834 Family Uncharacterised conserved protein UCP026306

1 GO Annotation

GO Term Gene Name
GO:0003824 IPR001736

1 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR001736

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
441825 D8RMV6 PAC:15410958 Selaginella moellendorffii 801  
165923 D8QXW1 PAC:15417215 Selaginella moellendorffii 804  
107537 D8S3H9 PAC:15421378 Selaginella moellendorffii 1019  
82084 D8QZ93 PAC:15408149 Selaginella moellendorffii 810  
153581 D8S963 PAC:15423478 Selaginella moellendorffii 834  
89049 D8RBB6 PAC:15406261 Selaginella moellendorffii 784  
evm.model.supercontig_10.255 PAC:16404621 Carica papaya 808  
evm.model.supercontig_127.37 PAC:16407400 Carica papaya 515  
evm.model.supercontig_131.50 PAC:16408046 Carica papaya 550  
evm.model.supercontig_18.175 PAC:16411321 Carica papaya 721  
evm.model.supercontig_259.1 PAC:16415014 Carica papaya 751  
evm.model.supercontig_26.257 PAC:16415202 Carica papaya 844  
evm.model.supercontig_29.28 PAC:16416234 Carica papaya 661  
evm.model.supercontig_48.121 PAC:16420753 Carica papaya 1100  
evm.model.supercontig_50.148 PAC:16421608 Carica papaya 769  
evm.model.supercontig_6.316 PAC:16423505 Carica papaya 654  
29726.m004097 B9RTA5 PAC:16806807 Ricinus communis 1117  
29784.m000369 B9SXC3 PAC:16808472 Ricinus communis 857  
29841.m002847 B9RV56 PAC:16810560 Ricinus communis 808  
29848.m004537 B9RNV6 PAC:16811193 Ricinus communis 516  
30128.m008869 B9RFF1 PAC:16818455 Ricinus communis 1077  
30170.m014290 B9R8F9 PAC:16822123 Ricinus communis 847  
30174.m008942 B9RDI4 PAC:16822585 Ricinus communis 1114  
30190.m011102 B9RC01 PAC:16823462 Ricinus communis 859  
35423.m000018 B9TCJ2 PAC:16826607 Ricinus communis 629  
28320.m001141 B9SET3 PAC:16800592 Ricinus communis 725  
28043.m000040 B9TAW8 PAC:16799815 Ricinus communis 501  
28694.m000682 B9SN47 PAC:16801544 Ricinus communis 762  
28725.m000311 B9SXF1 PAC:16801597 Ricinus communis 856  
Cucsa.363010.2 A0A0A0KBI5 PAC:16981015 Cucumis sativus 1095  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9242915
            8051126
            8732763
            8755242