| Type: | Family | Name: | DNA helicase (DNA repair), Rad3 type |
| Description: | Proteins in this family are DNA repair helicases, including Rad3/XPD family and Chl1/DDX11 family members. Rad3/XPD is a component of the TFIIH core complex, which is involved in excision repair of DNA damaged [, ]. DDX11/Chl1 is important for normal cell cycle progression [, ]. Defects in DDX11 are the cause of Warsaw breakage syndrome (WBRS). It is a syndrome characterised by severe microcephaly, pre- and postnatal growth retardation, facial dysmorphism and abnormal skin pigmentation []. | Short Name: | DNA_helicase_DNA-repair_Rad3 |
