Type: | Domain | Name: | Radical SAM, alpha/beta horseshoe |
Description: | Radical SAM domains catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. Evidence exists that these proteins generate a radical species by reductive cleavage of S:-adenosylmethionine (SAM) through an unusual Fe-S centre [, ].This entry represents radical SAM domains that form an alpha/beta horseshoe structure []. | Short Name: | rSAM_horseshoe |