Protein Domain : IPR006289

Type:  Family Name:  Transcription elongation factor, TFIIS
Description:  This entry represents transcription elongation factors of the IIS type. TFIIS is a component of RNA polymerase II preinitiation complexes, and is required for preinitiation complex assembly and stability []. The association of TFIIS with a promoter depends on functional preinitiation complex components including Mediator and the SAGA complex []. TFIIS is composed of three domains: domain 1 forms a 4-helical bundle that appears to bind certain initiation factors; domain 2 forms a 3-helical bundle and is required for Pol II binding; domain 3 forms a zinc ribbon and is essential for stimulation of RNA cleavage [, ]. Short Name:  TFSII
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0 Child Features

3 Contains

DB identifier Type Name
IPR003617 Domain Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
IPR001222 Domain Zinc finger, TFIIS-type
IPR017890 Domain Transcription elongation factor S-IIM

1 Cross References

Identifier
TIGR01385

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003676 IPR006289
GO:0006351 IPR006289
GO:0006355 IPR006289
GO:0005634 IPR006289

4 Ontology Annotations

GO Term Gene Name
GO:0003676 IPR006289
GO:0006351 IPR006289
GO:0006355 IPR006289
GO:0005634 IPR006289

1 Parent Features

DB identifier Type Name
IPR016492 Family Transcription elongation factor, TFIIS-related

507 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
437865 D8QRJ9 PAC:15421239 Selaginella moellendorffii 303  
evm.model.supercontig_86.75 PAC:16427631 Carica papaya 368  
29729.m002388 B9S4H1 PAC:16807037 Ricinus communis 330  
29915.m000481 B9SRT6 PAC:16813496 Ricinus communis 342  
Cucsa.325950.1 A0A0A0KDH9 PAC:16978014 Cucumis sativus 369  
orange1.1g017145m PAC:18106880 Citrus sinensis 376  
orange1.1g035641m A0A067DTX2 PAC:18097837 Citrus sinensis 314  
AT2G38560.1 Q9ZVH8 PAC:19640290 Arabidopsis thaliana 378  
Thhalv10016682m V4LPQ9 PAC:20181050 Eutrema salsugineum 433  
Thhalv10016797m V4NZY7 PAC:20181051 Eutrema salsugineum 381  
Ciclev10011982m V4UTA3 PAC:20796377 Citrus clementina 375  
Ciclev10024181m V4VT75 PAC:20811268 Citrus clementina 314  
Lus10014178 PAC:23152954 Linum usitatissimum 359  
Lus10025131 PAC:23167745 Linum usitatissimum 365  
Lus10034247 PAC:23176023 Linum usitatissimum 303  
Lus10025215 PAC:23157386 Linum usitatissimum 365  
Lus10022735 PAC:23178557 Linum usitatissimum 358  
Potri.016G138100.2 PAC:27012798 Populus trichocarpa 334  
Potri.016G138100.1 A0A2K1XFA9 PAC:27012797 Populus trichocarpa 350  
Potri.006G109300.2 A0A2K2A087 PAC:27004253 Populus trichocarpa 352  
Potri.006G109300.1 A0A2K2A087 PAC:27004252 Populus trichocarpa 352  
Gorai.005G003700.1 A0A0D2S8U1 PAC:26804145 Gossypium raimondii 332  
Gorai.006G235600.1 A0A0D2S193 PAC:26830936 Gossypium raimondii 366  
Gorai.011G124500.2 A0A0D2UT47 PAC:26807545 Gossypium raimondii 364  
Gorai.011G124500.1 A0A0D2UT47 PAC:26807544 Gossypium raimondii 364  
Gorai.011G124500.3 A0A0D2RLC8 PAC:26807546 Gossypium raimondii 317  
191995 C1NA42 PAC:27343939 Micromonas pusilla CCMP1545 325  
Thecc1EG045561t1 A0A061FSC5 PAC:27442445 Theobroma cacao 347  
Thecc1EG019685t1 A0A061EQ24 PAC:27452572 Theobroma cacao 367  
Migut.F00569.1.p A0A022PWF6 PAC:28933312 Mimulus guttatus 364  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17913884
            17901206
            16648364
            10940308