Protein Domain : IPR006634

Type:  Domain Name:  TRAM/LAG1/CLN8 homology domain
Description:  TLC is a protein domain with at least 5 transmembrane alpha-helices. Lag1p and Lac1p are essential foracyl-CoA-dependent ceramide synthesis [], TRAM is a subunitof the translocon and the CLN8 gene is mutated in Northern epilepsy syndrome. Proteins containing this domain may possessmultiple functions such as lipid trafficking, metabolism, or sensing. Trh homologues possess additionalhomeobox domains []. Short Name:  TLC-dom
Paste the following link

0 Child Features

0 Contains

3 Cross Referencess

Identifier
PF03798
PS50922
SM00724

2 Found Ins

DB identifier Type Name
IPR016439 Family Ceramide synthase component Lag1/Lac1
IPR016447 Family Translocation associated membrane protein

1 GO Annotation

GO Term Gene Name
GO:0016021 IPR006634

1 Ontology Annotations

GO Term Gene Name
GO:0016021 IPR006634

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
137631 D8TDZ7 PAC:15421400 Selaginella moellendorffii 261  
78320 D8QUF1 PAC:15420717 Selaginella moellendorffii 322  
420762 D8SD13 PAC:15415280 Selaginella moellendorffii 308  
407236 D8R4D3 PAC:15417406 Selaginella moellendorffii 285  
439306 D8R3G5 PAC:15423117 Selaginella moellendorffii 270  
236217 D8T6G1 PAC:15407338 Selaginella moellendorffii 208  
77830 D8QRS3 PAC:15421551 Selaginella moellendorffii 259  
75226 D8QQ54 PAC:15411267 Selaginella moellendorffii 227  
170071 D8RDJ6 PAC:15402951 Selaginella moellendorffii 294  
evm.TU.contig_36007.1 PAC:16430757 Carica papaya 246  
evm.TU.contig_45863.1 PAC:16432233 Carica papaya 64  
evm.model.supercontig_135.44 PAC:16408284 Carica papaya 273  
evm.model.supercontig_2.246 PAC:16412615 Carica papaya 248  
evm.model.supercontig_43.9 PAC:16420052 Carica papaya 231  
evm.model.supercontig_53.9 PAC:16422318 Carica papaya 308  
evm.model.supercontig_62.10 PAC:16423895 Carica papaya 326  
evm.model.supercontig_64.93 PAC:16424331 Carica papaya 190  
evm.model.supercontig_99.8 PAC:16429312 Carica papaya 226  
29801.m003184 B9RYI1 PAC:16809034 Ricinus communis 315  
29907.m000628 B9SK69 PAC:16812736 Ricinus communis 267  
29908.m006136 B9RJ39 PAC:16812954 Ricinus communis 281  
29929.m004733 B9RMM8 PAC:16813972 Ricinus communis 249  
29993.m001035 B9S2Z8 PAC:16815319 Ricinus communis 266  
30125.m001244 B9RRN6 PAC:16818111 Ricinus communis 275  
30170.m014091 B9R7Z6 PAC:16821927 Ricinus communis 233  
30174.m009049 B9RE82 PAC:16822690 Ricinus communis 308  
30190.m010980 B9RBN2 PAC:16823343 Ricinus communis 218  
36771.m000012 B9TAI2 PAC:16826964 Ricinus communis 265  
Cucsa.118780.1 A0A0A0KAK8 PAC:16960885 Cucumis sativus 260  
Cucsa.118780.2 A0A0A0KAK8 PAC:16960886 Cucumis sativus 260  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9872981
            11694577