Protein Domain : IPR002113

Type:  Family Name:  Adenine nucleotide translocator 1
Description:  A variety of substrate carrier proteins that are involved in energy transfer are found in the inner mitochondrial membrane [, , , ]. Such proteins include:ADP,ATP carrier protein (ADP/ATP translocase); 2-oxoglutarate/malate carrier protein; phosphate carrier protein; tricarboxylate transport protein (orcitrate transport protein); Graves disease carrier protein; yeast mitochondrial proteins MRS3 and MRS4; yeast mitochondrial FAD carrier protein;and many others.Sequence analysis of selected members of the carrier protein family has suggested the presence of six transmembrane (TM) domains, with varyingdegrees of sequence conservation and hydrophilicity []. The TM regions,and adjacent hydrophilic loops, are more highly conserved than other regions of the proteins []. All members of the family appear to consistof a tripartite structure, each of the repeated segments being ~100 residues in length []. Each repeat contains two TM domains, the first being morehydrophobic, with conserved glycyl and prolyl residues. Five of the six TM domains are followed by the conserved sequence (D/E)-Hy(K/R), where - denotesany residue and Hy is a hydrophobic position [].Mitochondrial ADP/ATP translocase, an abundant component of the inner membrane, carries ATP from the matrix into the inter-membrane space andtransports ADP back []. The protein is an integral membrane protein thatfunctions as a homodimer. Short Name:  Aden_trnslctor

0 Child Features

1 Contains

DB identifier Type Name
IPR018108 Repeat Mitochondrial substrate/solute carrier

1 Cross References

Identifier
PR00927

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0005215 IPR002113
GO:0006810 IPR002113
GO:0055085 IPR002113
GO:0005743 IPR002113

4 Ontology Annotations

GO Term Gene Name
GO:0005215 IPR002113
GO:0006810 IPR002113
GO:0055085 IPR002113
GO:0005743 IPR002113

1 Parent Features

DB identifier Type Name
IPR002067 Family Mitochondrial carrier protein

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
134740 D8T949 PAC:15413588 Selaginella moellendorffii 227  
236748 D8TCW3 PAC:15411399 Selaginella moellendorffii 302  
109762 D8S6L7 PAC:15406558 Selaginella moellendorffii 365  
230650 D8R367 PAC:15415463 Selaginella moellendorffii 299  
437328 D8QQ73 PAC:15417418 Selaginella moellendorffii 351  
235544 D8SYR4 PAC:15406832 Selaginella moellendorffii 300  
evm.model.supercontig_3.245 PAC:16416530 Carica papaya 315  
evm.model.supercontig_7.188 PAC:16425095 Carica papaya 212  
evm.model.supercontig_83.66 PAC:16427207 Carica papaya 379  
evm.model.supercontig_84.70 PAC:16427355 Carica papaya 180  
evm.model.supercontig_883.2 PAC:16427868 Carica papaya 385  
29794.m003303 B9RRQ6 PAC:16808664 Ricinus communis 326  
29889.m003333 B9RZU2 PAC:16812279 Ricinus communis 270  
29983.m003162 B9RVW7 PAC:16814930 Ricinus communis 379  
30138.m003936 B9RLK1 PAC:16819304 Ricinus communis 368  
30169.m006421 B9RIA6 PAC:16821221 Ricinus communis 363  
30169.m006422 B9RIA7 PAC:16821222 Ricinus communis 392  
29212.m000185 B9T0Z2 PAC:16802476 Ricinus communis 385  
Cucsa.395080.1 A0A0A0LKE3 PAC:16983301 Cucumis sativus 325  
Cucsa.396010.1 PAC:16983459 Cucumis sativus 423  
Cucsa.396020.1 PAC:16983460 Cucumis sativus 411  
Cucsa.113450.1 A0A0A0LSW7 PAC:16960331 Cucumis sativus 315  
Cucsa.346070.1 A0A0A0K2E6 PAC:16979598 Cucumis sativus 378  
Cucsa.346070.2 A0A0A0K2E6 PAC:16979599 Cucumis sativus 378  
orange1.1g024275m A0A067FIJ1 PAC:18131040 Citrus sinensis 270  
orange1.1g016168m A0A067F5B1 PAC:18124201 Citrus sinensis 394  
orange1.1g016996m A0A067DVY8 PAC:18103473 Citrus sinensis 379  
orange1.1g016980m A0A067DVY8 PAC:18103474 Citrus sinensis 379  
orange1.1g017022m A0A067DVY8 PAC:18103475 Citrus sinensis 379  
orange1.1g016663m A0A067H743 PAC:18101414 Citrus sinensis 385  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8487299
            8140286
            2158156
            8325039
            2541251