Protein Domain : IPR014751

Type:  Domain Name:  DNA repair protein XRCC4, C-terminal
Description:  XRCC4 is essential for non-homologous DNA end joining (NHDJ) in eukaryotes, which is required for double-strand break repair, and V(D)J recombination in immunoglobulin and T-cell receptor genes. XRCC4 forms a complex with DNA ligase IV, and acts as a regulatory element required for the stability and activity of the ligase. XRCC4 forms an elongated dumb-bell-like tetramer consisting of a C-terminal stalk that interacts with DNA ligase IV and an N-terminal globular head. The C-terminal oligomerisation domain consists of oligomers of short identical helices that form parallel coiled-coils [, ]. Short Name:  XRCC4_C
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0 Child Features

0 Contains

1 Cross References

Identifier
G3DSA:1.20.5.370

1 Found In

DB identifier Type Name
IPR010585 Family DNA repair protein XRCC4

3 GO Annotations

GO Term Gene Name
GO:0003677 IPR014751
GO:0006302 IPR014751
GO:0006310 IPR014751

3 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR014751
GO:0006302 IPR014751
GO:0006310 IPR014751

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
432266 D8T890 PAC:15402114 Selaginella moellendorffii 654  
271069 D8RT81 PAC:15420215 Selaginella moellendorffii 233  
81609 D8R0G9 PAC:15409700 Selaginella moellendorffii 127  
180358 D8SJX8 PAC:15412526 Selaginella moellendorffii 863  
407756 D8R6N0 PAC:15421183 Selaginella moellendorffii 460  
439685 D8R519 PAC:15403305 Selaginella moellendorffii 369  
447568 PAC:15403781 Selaginella moellendorffii 2791  
402651 D8QML6 PAC:15405830 Selaginella moellendorffii 283  
evm.model.supercontig_1379.1 PAC:16408437 Carica papaya 310  
evm.model.supercontig_14.68 PAC:16408817 Carica papaya 148  
evm.model.supercontig_162.11 PAC:16410232 Carica papaya 156  
evm.model.supercontig_50.80 PAC:16421705 Carica papaya 313  
evm.model.supercontig_55.150 PAC:16422540 Carica papaya 278  
evm.model.supercontig_58.53 PAC:16423026 Carica papaya 224  
evm.model.supercontig_6.294 PAC:16423480 Carica papaya 420  
evm.model.supercontig_768.4 PAC:16426052 Carica papaya 477  
29827.m002598 B9S1L7 PAC:16810030 Ricinus communis 455  
29841.m002774 B9RUY5 PAC:16810489 Ricinus communis 428  
29844.m003159 B9RTD9 PAC:16810867 Ricinus communis 265  
29903.m000185 B9SPU5 PAC:16812530 Ricinus communis 271  
29904.m003039 B9RWS0 PAC:16812682 Ricinus communis 713  
29913.m000156 B9T617 PAC:16813469 Ricinus communis 61  
30073.m002282 B9S239 PAC:16816865 Ricinus communis 242  
30174.m009080 B9REB3 PAC:16822721 Ricinus communis 198  
50378.m000013 B9TBB1 PAC:16828261 Ricinus communis 487  
29625.m000689 B9SRV7 PAC:16803841 Ricinus communis 77  
29680.m001669 B9S7I6 PAC:16805503 Ricinus communis 116  
29670.m000146 B9T2R3 PAC:16805274 Ricinus communis 252  
Cucsa.322780.1 A0A0A0L3N0 PAC:16977824 Cucumis sativus 418  
Cucsa.322780.5 PAC:16977828 Cucumis sativus 405  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11702069
            11080143