Protein Domain : IPR000594

Type:  Domain Name:  THIF-type NAD/FAD binding fold
Description:  This domain is a NAD/FAD-binding fold found in ubiquitin activating E1 family and members of the bacterial ThiF/MoeB/HesA family. It is repeated in Ubiquitin-activating enzyme E1 [, , ]. Ubiquitin-activating enzyme (E1 enzyme) [, ] activates ubiquitin by firstadenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding anubiquitin-E1 thiolester and free AMP. Later the ubiquitin moiety is transferred to a cysteine residue on one of the many forms of ubiquitin-conjugating enzymes (E2). Short Name:  ThiF_NAD_FAD-bd
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF00899
SSF69572

7 Found Ins

DB identifier Type Name
IPR006285 Family Ubiquitin-like modifier-activating enzyme Atg7
IPR018075 Family Ubiquitin-activating enzyme, E1
IPR000011 Family Ubiquitin/SUMO-activating enzyme E1
IPR012730 Family Molybdopterin synthase sulfurylase MoeB
IPR012729 Family Thiamine biosynthesis protein ThiF
IPR012731 Family Thiazole biosynthesis adenylyltransferase ThiF
IPR022500 Family ParB-related, ThiF-related cassette, ThiF

1 GO Annotation

GO Term Gene Name
GO:0008641 IPR000594

1 Ontology Annotations

GO Term Gene Name
GO:0008641 IPR000594

1 Parent Features

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
174709 D8RVM4 PAC:15419921 Selaginella moellendorffii 449  
103350 D8RVZ4 PAC:15408228 Selaginella moellendorffii 542  
113369 D8SC95 PAC:15415597 Selaginella moellendorffii 329  
116179 D8SG67 PAC:15422741 Selaginella moellendorffii 407  
179776 D8SHI4 PAC:15412414 Selaginella moellendorffii 1021  
85168 D8R5Z7 PAC:15417746 Selaginella moellendorffii 422  
164297 D8QNA7 PAC:15409089 Selaginella moellendorffii 698  
77030 D8QRN9 PAC:15415601 Selaginella moellendorffii 399  
437713 D8QP30 PAC:15420469 Selaginella moellendorffii 407  
145914 D8RCF4 PAC:15402715 Selaginella moellendorffii 1007  
131125 D8T3J7 PAC:15422372 Selaginella moellendorffii 590  
evm.model.supercontig_1026.1 PAC:16404875 Carica papaya 633  
evm.model.supercontig_1141.1 PAC:16406164 Carica papaya 193  
evm.model.supercontig_116.80 PAC:16406341 Carica papaya 397  
evm.model.supercontig_12.256 PAC:16406810 Carica papaya 477  
evm.model.supercontig_13.116 PAC:16407621 Carica papaya 425  
evm.model.supercontig_147.13 PAC:16409186 Carica papaya 449  
evm.model.supercontig_2.388 PAC:16412772 Carica papaya 960  
evm.model.supercontig_2.389 PAC:16412773 Carica papaya 1096  
evm.model.supercontig_7.54 PAC:16425216 Carica papaya 540  
evm.model.supercontig_807.6 PAC:16426846 Carica papaya 74  
evm.model.supercontig_87.77 PAC:16427748 Carica papaya 523  
29762.m000496 B9STZ8 PAC:16808144 Ricinus communis 467  
29820.m000987 B9SKZ1 PAC:16809647 Ricinus communis 1100  
29844.m003336 B9RTW5 PAC:16811043 Ricinus communis 449  
29900.m001609 B9S996 PAC:16812487 Ricinus communis 710  
29932.m000611 B9SKU8 PAC:16814096 Ricinus communis 1107  
30131.m007087 B9RH95 PAC:16818912 Ricinus communis 644  
30147.m014476 B9RAD1 PAC:16820485 Ricinus communis 321  
30147.m014505 B9RAF9 PAC:16820513 Ricinus communis 428  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1647207
            1656558
            11713534
            15660128
            18662542