Protein Domain : IPR003661

Type:  Domain Name:  Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
Description:  This entry represents the dimerisation and phosphoacceptor domain found in some histidine kinases. Signal transducing histidine kinases are the key elements in two-component signal transduction systems, which control complex processes such as the initiation of development in microorganisms []. Examples of histidine kinases are EnvZ, which plays a central role in osmoregulation []. Histidine kinases usually have an N-terminal ligand-binding domain and a C-terminal kinase domain, but other domains may also be present. The kinase domain is responsible for the autophosphorylation of the histidine with ATP, the phosphotransfer from the kinase to an aspartate of the response regulator, and the phosphotransfer from aspartyl phosphate back to ADP or to water []. The homodimeric domain includes the site of histidine autophosphorylation and phosphate transfer reactions. The structure of the homodimeric domain comprises a closed, four-helical bundle with a left-handed twist, formed by two identical alpha-hairpin subunits. Short Name:  HisK_dim/P
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0 Child Features

0 Contains

4 Cross Referencess

Identifier
PF00512
SM00388
G3DSA:1.10.287.130
SSF47384

14 Found Ins

DB identifier Type Name
IPR012129 Family Phytochrome A/B/C/D/E
IPR001294 Family Phytochrome
IPR014525 Family Signal transduction histidine kinase, hybrid-type, ethylene sensor
IPR014310 Family Signal transduction histidine kinase, phosphate regulon sensor PhoR
IPR006290 Family Heavy metal sensor kinase
IPR014409 Family Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB
IPR017181 Family Signal transduction histidine kinase, CHASE2/PAS sensor domain-containing, predicted
IPR014265 Family Signal transduction histidine kinase, PEP-CTERM system, putative
IPR017232 Family Signal transduction histidine kinase, nitrogen fixation and metabolism regulator
IPR014302 Family Signal transduction histidine kinase, TMAO sensor TorS
IPR017116 Family Signal transduction histidine kinase, PgtB
IPR017055 Family Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator)
IPR022510 Family Sortase system, histidine kinase
IPR008358 Family Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB

2 GO Annotations

GO Term Gene Name
GO:0000155 IPR003661
GO:0007165 IPR003661

2 Ontology Annotations

GO Term Gene Name
GO:0000155 IPR003661
GO:0007165 IPR003661

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
162543 D8TAU9 PAC:15405347 Selaginella moellendorffii 440  
96794 D8RLK2 PAC:15410241 Selaginella moellendorffii 1116  
267662 D8RRE6 PAC:15412834 Selaginella moellendorffii 736  
101176 PAC:15423208 Selaginella moellendorffii 432  
104037 D8RWN3 PAC:15408855 Selaginella moellendorffii 1086  
405045 PAC:15410073 Selaginella moellendorffii 1067  
152221 D8S3K5 PAC:15418237 Selaginella moellendorffii 905  
3025 PAC:15409785 Selaginella moellendorffii 328  
109384 PAC:15403497 Selaginella moellendorffii 465  
110685 D8S7K1 PAC:15409088 Selaginella moellendorffii 747  
111212 D8S949 PAC:15408755 Selaginella moellendorffii 325  
112002 D8S9C6 PAC:15410225 Selaginella moellendorffii 108  
117801 D8SJA5 PAC:15408533 Selaginella moellendorffii 283  
84050 D8R3C4 PAC:15414122 Selaginella moellendorffii 229  
84824 D8R4B8 PAC:15420072 Selaginella moellendorffii 740  
20385 PAC:15406107 Selaginella moellendorffii 792  
446134 D8SNY8 PAC:15420176 Selaginella moellendorffii 303  
230881 D8R4U9 PAC:15417001 Selaginella moellendorffii 605  
163842 PAC:15410696 Selaginella moellendorffii 609  
73679 D8QNR8 PAC:15408474 Selaginella moellendorffii 305  
404011 D8QTA6 PAC:15406954 Selaginella moellendorffii 236  
231095 D8R9F4 PAC:15413947 Selaginella moellendorffii 965  
16166 D8R9G6 PAC:15414985 Selaginella moellendorffii 101  
14315 D8RD50 PAC:15410527 Selaginella moellendorffii 272  
430194 D8T8N0 PAC:15417884 Selaginella moellendorffii 678  
161430 D8T691 PAC:15401681 Selaginella moellendorffii 1143  
evm.model.supercontig_136.20 PAC:16408309 Carica papaya 1045  
evm.model.supercontig_151.32 PAC:16409550 Carica papaya 637  
evm.model.supercontig_17.112 PAC:16410603 Carica papaya 1112  
evm.model.supercontig_18.35 PAC:16411420 Carica papaya 1511  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8868347
            10426948
            11145881