Protein Domain : IPR009080

Type:  Domain Name:  Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
Description:  Aminoacyl-tRNA synthetase (aaRS) is a key enzyme during protein biosynthesis. Each aaRS contains a catalytic central domain (CCD), responsible for activating amino acid, and an anticodon-binding domain (ABD), necessary for binding the anticodon in cognate tRNA. aaRSs are classified into class I and II (aaRS-I and aaRS-II) based on the topologies of CCDs. Whereas the structure of the CCDs is similar among the members of each of the two different aaRS classes, the ABDs are diverse in structure [].The synthetases specific for arginine, cysteine, glutamic acid, glutamine, isoleucine, leucine, methionine, tyrosine, tryptophan and valine belong to class I synthetases. The synthetases specific for alanine, asparagine, aspartic acid, glycine, histidine, lysine, phenylalanine, proline, serine, and threonine belong to class-II synthetases. Both classes of tRNA synthetases have been subdivided into three subclasses, designated Ia, Ib, Ic and IIa, IIb, IIc.This domain represents the anticodon binding domain (ABD) of class Ia aminoacyl-tRNA synthetases, and also matches the ABD of glycine tRNA synthetases. Short Name:  tRNAsynth_1a_anticodon-bd

3 Child Features

DB identifier Type Name
IPR008909 Domain DALR anticodon binding
IPR013155 Domain Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
IPR015273 Domain Cysteinyl-tRNA synthetase, class Ia, DALR

2 Contains

DB identifier Type Name
IPR008909 Domain DALR anticodon binding
IPR010663 Domain Zinc finger, FPG/IleRS-type

2 Cross Referencess

Identifier
G3DSA:1.10.730.10
SSF47323

2 Found Ins

DB identifier Type Name
IPR001278 Family Arginine-tRNA ligase
IPR020791 Family Leucine-tRNA ligase, archaeal

4 GO Annotations

GO Term Gene Name
GO:0000166 IPR009080
GO:0004812 IPR009080
GO:0005524 IPR009080
GO:0006418 IPR009080

4 Ontology Annotations

GO Term Gene Name
GO:0000166 IPR009080
GO:0004812 IPR009080
GO:0005524 IPR009080
GO:0006418 IPR009080

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
410808 D8RFX9 PAC:15408586 Selaginella moellendorffii 1108  
411187 D8RGU8 PAC:15406368 Selaginella moellendorffii 289  
413900 D8RQZ9 PAC:15418186 Selaginella moellendorffii 290  
141956 D8QWX7 PAC:15413568 Selaginella moellendorffii 960  
443981 D8S601 PAC:15417664 Selaginella moellendorffii 1031  
153639 D8S9D7 PAC:15401914 Selaginella moellendorffii 1155  
154280 D8SCM5 PAC:15401882 Selaginella moellendorffii 496  
421269 D8SEP7 PAC:15414407 Selaginella moellendorffii 855  
445517 D8SJ90 PAC:15420275 Selaginella moellendorffii 1155  
119009 D8SJX9 PAC:15408236 Selaginella moellendorffii 502  
157130 D8SPD3 PAC:15409754 Selaginella moellendorffii 1103  
140217 D8QP34 PAC:15405073 Selaginella moellendorffii 595  
427360 D8SZB8 PAC:15410349 Selaginella moellendorffii 184  
74165 D8QR04 PAC:15407494 Selaginella moellendorffii 347  
437676 D8QNT8 PAC:15419827 Selaginella moellendorffii 1707  
76727 D8QSZ8 PAC:15417941 Selaginella moellendorffii 578  
77212 D8QTN5 PAC:15417053 Selaginella moellendorffii 1096  
164891 D8QRU7 PAC:15413777 Selaginella moellendorffii 784  
426245 D8SVU0 PAC:15406519 Selaginella moellendorffii 305  
evm.model.supercontig_1.385 PAC:16404327 Carica papaya 272  
evm.model.supercontig_1.387 PAC:16404329 Carica papaya 618  
evm.model.supercontig_1077.2 PAC:16405415 Carica papaya 65  
evm.model.supercontig_113.23 PAC:16406032 Carica papaya 1077  
evm.model.supercontig_116.46 PAC:16406303 Carica papaya 804  
evm.model.supercontig_122.39 PAC:16407087 Carica papaya 819  
evm.model.supercontig_152.47 PAC:16409632 Carica papaya 975  
evm.model.supercontig_16.173 PAC:16410022 Carica papaya 864  
evm.model.supercontig_19.108 PAC:16411837 Carica papaya 333  
evm.model.supercontig_19.73 PAC:16412086 Carica papaya 487  
evm.model.supercontig_2.74 PAC:16412864 Carica papaya 1095  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15733854