Protein Domain : IPR020683

Type:  Domain Name:  Ankyrin repeat-containing domain
Description:  This entry represents the ankyrin repeat-containing domain. These domains contain multiple repeats of a beta(2)-alpha(2) motif. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes. The few known examples from prokaryotes and viruses may be the result of horizontal gene transfers []. The repeat has been found in proteins of diverse function such as transcriptional initiators, cell-cycle regulators, cytoskeletal, ion transporters and signal transducers. The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [, , , ]. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90oangle. The repeats stack together to form an L-shaped structure [, ]. Short Name:  Ankyrin_rpt-contain_dom
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0 Child Features

1 Contains

DB identifier Type Name
IPR002110 Repeat Ankyrin repeat

5 Cross Referencess

Identifier
PF11929
PF12796
PS50297
G3DSA:1.25.40.20
SSF48403

18 Found Ins

DB identifier Type Name
IPR017408 Family Arginine N-methyltransferase 2
IPR004729 Family Transient receptor potential channel
IPR008344 Family Transient receptor potential cation channel subfamily V member 5/6
IPR008347 Family Transient receptor potential channel, vanilloid 1-4
IPR005457 Family Transient receptor potential channel, canonical 1
IPR005460 Family Transient receptor potential channel, canonical 4
IPR005463 Family Transient receptor potential channel, canonical 7
IPR008345 Family Transient receptor potential channel, vanilloid 6
IPR022362 Family Neurogenic locus Notch 1
IPR020676 Family Death-associated protein kinase 1
IPR008348 Family Transient receptor potential channel, vanilloid 4
IPR017362 Family DNA-binding, RFXANK
IPR017401 Family Protein phosphatase 1 regulatory subunit 12A/B, chordates
IPR017417 Family Protein phosphatase 1, regulatory subunit 16A/B
IPR022331 Family Neurogenic locus Notch 3
IPR022336 Family Neurogenic locus Notch 2
IPR008297 Family Notch
IPR022355 Family Neurogenic locus Notch 4

0 GO Annotation

0 Ontology Annotations

0 Parent Features

65378 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
92587 D8RF13 PAC:15419276 Selaginella moellendorffii 332  
430531 D8T9P6 PAC:15420817 Selaginella moellendorffii 284  
95714 D8RL31 PAC:15406990 Selaginella moellendorffii 231  
228083 D8RLX4 PAC:15404632 Selaginella moellendorffii 162  
441660 D8RLS6 PAC:15409448 Selaginella moellendorffii 590  
441667 D8RLU7 PAC:15409450 Selaginella moellendorffii 982  
97739 D8RND7 PAC:15413029 Selaginella moellendorffii 395  
4909 D8QVX4 PAC:15419556 Selaginella moellendorffii 167  
4907 D8QVX2 PAC:15419554 Selaginella moellendorffii 141  
62282 D8QUL3 PAC:15417722 Selaginella moellendorffii 499  
77935 D8QUK1 PAC:15422348 Selaginella moellendorffii 543  
7175 D8QVW9 PAC:15422257 Selaginella moellendorffii 109  
173073 D8RP22 PAC:15411848 Selaginella moellendorffii 307  
413320 D8RP30 PAC:15413711 Selaginella moellendorffii 969  
232336 PAC:15418944 Selaginella moellendorffii 750  
141633 D8QXZ3 PAC:15411241 Selaginella moellendorffii 447  
175493 D8RYT9 PAC:15420739 Selaginella moellendorffii 531  
105905 D8S0G7 PAC:15418654 Selaginella moellendorffii 395  
106391 D8S1Q0 PAC:15417178 Selaginella moellendorffii 625  
107813 D8S3G9 PAC:15401376 Selaginella moellendorffii 435  
50132 D8S5Z7 PAC:15403700 Selaginella moellendorffii 908  
110129 D8S6B5 PAC:15405059 Selaginella moellendorffii 516  
418639 D8S6P1 PAC:15408167 Selaginella moellendorffii 562  
418760 D8S6B2 PAC:15409065 Selaginella moellendorffii 316  
418698 D8S6V6 PAC:15408328 Selaginella moellendorffii 412  
444080 D8S6B3 PAC:15413764 Selaginella moellendorffii 156  
167008 D8R0R2 PAC:15416174 Selaginella moellendorffii 161  
405610 D8QZ49 PAC:15414682 Selaginella moellendorffii 404  
81884 D8QZ57 PAC:15411483 Selaginella moellendorffii 475  
5251 D8S9U6 PAC:15417237 Selaginella moellendorffii 194  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8108379
            8875926
            9353127
            9461436
            9865693
            12461176