Protein Domain : IPR005894

Type:  Family Name:  Daunorubicin resistance ABC transporter ATP-binding subunit DrrA
Description:  ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily, which uses the hydrolysis of ATP to energise diverse biological systems. ABC transporters minimally consist of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These can be found on the same protein or on two different ones. Most ABC transporters function as a dimer and therefore are constituted of four domains, two ABC modules and two TMDs.This entry represents the daunorubicin resistance ABC transporter ATP binding subunit DrrA, which is found in bacteria and archaea. DrrA is part of the ABC transporter complex DrrABC (composed of two ATP-binding proteins (DrrA) and two transmembrane proteins (DrrB and DrrC)). The DrrABC complex functions as an ATP dependent antiporter and is involved in doxorubicin and daunorubicin efflux [, ]. Short Name:  DrrA
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0 Child Features

2 Contains

DB identifier Type Name
IPR003439 Domain ABC transporter-like
IPR017871 Conserved_site ABC transporter, conserved site

1 Cross References

Identifier
TIGR01188

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005524 IPR005894
GO:0043215 IPR005894
GO:1900753 IPR005894

3 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR005894
GO:0043215 IPR005894
GO:1900753 IPR005894

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s58_70V3.1.p PAC:32929827 Physcomitrium patens 590  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            20158521
            9006006