Protein Domain : IPR005892

Type:  Family Name:  Glycine betaine transport ATP-binding subunit
Description:  This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits this transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA [, , , ]. A gene library from Lactococcus lactisfunctionally complements an Escherichia coliproU mutant. The complementing locus is similar to a opuA locus in Bacillus subtilis. This clarifies the differences in nomenclature. Short Name:  Gly-betaine_transp_ATP-bd
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0 Child Features

3 Contains

DB identifier Type Name
IPR003439 Domain ABC transporter-like
IPR000644 Domain CBS domain
IPR017871 Conserved_site ABC transporter, conserved site

1 Cross References

Identifier
TIGR01186

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0005524 IPR005892
GO:0031460 IPR005892
GO:0016020 IPR005892

3 Ontology Annotations

GO Term Gene Name
GO:0005524 IPR005892
GO:0031460 IPR005892
GO:0016020 IPR005892

0 Parent Features

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s30_750V3.1.p PAC:32948457 Physcomitrium patens 908  
Brdisv1pangenome1007390m.p PAC:33607784 Brachypodium distachyon Pangenome 292  
Brdisv1pangenome1009642m.p PAC:33624080 Brachypodium distachyon Pangenome 427  
Brdisv1BdTR11A1042273m.p PAC:35688661 Brachypodium distachyon BdTR11a 292  
Brdisv1BdTR11A1042591m.p PAC:35688189 Brachypodium distachyon BdTR11a 219  
Brdisv1BdTR11A1040663m.p PAC:35689274 Brachypodium distachyon BdTR11a 427  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7898450
            19114512
            10939245
            16645306