Protein Domain : IPR021154

Type:  Family Name:  H/ACA ribonucleoprotein complex, subunit Gar1
Description:  H/ACA ribonucleoprotein particles (RNPs) are a family of RNA pseudouridine synthases that specify modification sites through guide RNAs. More than 100 mammalian H/ACA RNAs form an equal number of ribonucleoproteins (RNPs) by associating with the same four core proteins: Cbf5, Gar1, Nhp2 and Nop10. The function of these H/ACA RNPs is essential for biogenesis of the ribosome, splicing of precursor mRNAs (pre-mRNAs), maintenance of telomeres and probably for additional cellular processes []. Recent crystal structures of archaeal H/ACA protein complexes show how the same four proteins accommodate >100 distinct but related H/ACA RNAs []. The complex contains a stable core composed of Cbf5 and Nop10, to which Gar1 and Nhp2 subsequently bind, the complex interacts with snoRNAs [].This entry represents Gar1. Short Name:  H/ACA_rnp_Gar1
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PTHR23237
PD020235

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0001522 IPR021154
GO:0042254 IPR021154
GO:0031429 IPR021154

3 Ontology Annotations

GO Term Gene Name
GO:0001522 IPR021154
GO:0042254 IPR021154
GO:0031429 IPR021154

1 Parent Features

DB identifier Type Name
IPR007504 Family H/ACA ribonucleoprotein complex, subunit Gar1/Naf1

446 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
266974 D8R5G8 PAC:15412234 Selaginella moellendorffii 191  
evm.model.supercontig_51.114 PAC:16421778 Carica papaya 158  
29950.m001133 B9SHF9 PAC:16814408 Ricinus communis 194  
Cucsa.024070.1 A0A0A0KWF0 PAC:16951992 Cucumis sativus 194  
Cucsa.024070.2 PAC:16951993 Cucumis sativus 187  
Cucsa.024070.3 PAC:16951994 Cucumis sativus 187  
orange1.1g033397m A0A067EMB5 PAC:18116157 Citrus sinensis 120  
orange1.1g029223m A0A067EVR8 PAC:18116153 Citrus sinensis 197  
orange1.1g032119m A0A067EIY1 PAC:18116154 Citrus sinensis 147  
orange1.1g032083m A0A067EUZ0 PAC:18116155 Citrus sinensis 147  
orange1.1g032478m A0A067EIM8 PAC:18116156 Citrus sinensis 140  
AT5G18180.1 Q9FK53 PAC:19666495 Arabidopsis thaliana 189  
AT3G03920.1 Q8VZT0 PAC:19664572 Arabidopsis thaliana 202  
Thhalv10021561m V4NSP4 PAC:20183752 Eutrema salsugineum 196  
Thhalv10014755m V4LPN9 PAC:20206145 Eutrema salsugineum 191  
Lus10020289 PAC:23144068 Linum usitatissimum 194  
Potri.019G034900.2 PAC:27026896 Populus trichocarpa 176  
Potri.019G034900.1 A0A2K1WNY7 PAC:27026895 Populus trichocarpa 189  
Potri.013G058400.3 B9I5Y3 PAC:26993920 Populus trichocarpa 204  
Potri.013G058400.2 B9I5Y3 PAC:26993919 Populus trichocarpa 204  
Potri.013G058400.1 B9I5Y3 PAC:26993921 Populus trichocarpa 204  
Gorai.004G244500.1 A0A0D2RA46 PAC:26775314 Gossypium raimondii 193  
Gorai.007G343400.1 A0A0D2SP68 PAC:26778454 Gossypium raimondii 194  
30690 I0YQ94 PAC:27395056 Coccomyxa subellipsoidea C-169 199  
11721 C1MVY1 PAC:27341109 Micromonas pusilla CCMP1545 85  
107421 C1EBZ3 PAC:27401155 Micromonas sp RCC299 191  
Thecc1EG026465t1 A0A061F3J0 PAC:27423313 Theobroma cacao 193  
Migut.J01888.1.p A0A022RM12 PAC:28940389 Mimulus guttatus 197  
Araha.8689s0012.1.p PAC:28852161 Arabidopsis halleri 127  
Araha.51494s0005.1.p PAC:28859249 Arabidopsis halleri 201  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16943774
            16647858
            19917616