Protein Domain : IPR017476

Type:  Family Name:  UDP-glucose/GDP-mannose dehydrogenase
Description:  Enzymes in this family catalyse the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase () [], GDP-mannose 6-dehydrogenase () [], UDP-N-acetylglucosamine 6-dehydrogenase () [], UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase [], UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [] and UDP-N-acetyl-D-mannosamine dehydrogenase []. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three domains, , , and for the N-terminal, central, and C-terminal regions respectively. Short Name:  UDP-Glc/GDP-Man
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4 Child Features

DB identifier Type Name
IPR028356 Family UDP-glucose 6-dehydrogenase, eukaryotic type
IPR028359 Family UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase
IPR028357 Family UDP-glucose 6-dehydrogenase, bacterial type
IPR028358 Family GDP-mannose 6-dehydrogenase

5 Contains

DB identifier Type Name
IPR001732 Domain UDP-glucose/GDP-mannose dehydrogenase, N-terminal
IPR014026 Domain UDP-glucose/GDP-mannose dehydrogenase, dimerisation
IPR014027 Domain UDP-glucose/GDP-mannose dehydrogenase, C-terminal
IPR016040 Domain NAD(P)-binding domain
IPR008927 Domain 6-phosphogluconate dehydrogenase C-terminal domain-like

3 Cross Referencess

Identifier
PTHR11374
PIRSF000124
TIGR03026

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0016616 IPR017476
GO:0055114 IPR017476

2 Ontology Annotations

GO Term Gene Name
GO:0016616 IPR017476
GO:0055114 IPR017476

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
84327 D8R4C3 PAC:15416273 Selaginella moellendorffii 481  
evm.model.supercontig_1.107 PAC:16404019 Carica papaya 407  
evm.model.supercontig_14.161 PAC:16408660 Carica papaya 252  
evm.model.supercontig_94.20 PAC:16428756 Carica papaya 481  
30138.m004004 B9RLR7 PAC:16819370 Ricinus communis 480  
30174.m009127 B9REG0 PAC:16822767 Ricinus communis 480  
30174.m009131 B9REG4 PAC:16822771 Ricinus communis 480  
30174.m009132 B9REG5 PAC:16822772 Ricinus communis 480  
30998.m000028 B9TJE4 PAC:16824749 Ricinus communis 202  
33997.m000015 B9TGX3 PAC:16826060 Ricinus communis 435  
35039.m000020 B9THJ7 PAC:16826461 Ricinus communis 427  
35949.m000025 B9TDI3 PAC:16826805 Ricinus communis 170  
47378.m000014 B9TPJ7 PAC:16827988 Ricinus communis 216  
Cucsa.198120.1 A0A0A0LRT1 PAC:16968540 Cucumis sativus 480  
Cucsa.198120.2 A0A0A0LRT1 PAC:16968541 Cucumis sativus 480  
Cucsa.273150.1 PAC:16973778 Cucumis sativus 480  
orange1.1g011641m A0A067FZI2 PAC:18135246 Citrus sinensis 480  
orange1.1g017997m A0A067FZD9 PAC:18135247 Citrus sinensis 362  
orange1.1g011650m A0A067GTQ8 PAC:18101651 Citrus sinensis 480  
orange1.1g011654m A0A067EHN5 PAC:18134952 Citrus sinensis 480  
AT5G15490.1 Q9LF33 PAC:19673268 Arabidopsis thaliana 480  
AT5G39320.1 Q9FM01 PAC:19669272 Arabidopsis thaliana 480  
AT3G29360.1 Q9LIA8 PAC:19660213 Arabidopsis thaliana 480  
AT3G29360.2 Q9LIA8 PAC:19660214 Arabidopsis thaliana 480  
AT1G26570.1 Q9FZE1 PAC:19649696 Arabidopsis thaliana 481  
Thhalv10027800m V4LTH3 PAC:20189932 Eutrema salsugineum 369  
Thhalv10013414m V4LNY4 PAC:20206572 Eutrema salsugineum 480  
Thhalv10013412m V4LNY4 PAC:20206573 Eutrema salsugineum 480  
Thhalv10010007m V4MRB3 PAC:20185816 Eutrema salsugineum 481  
Thhalv10004110m V4MM75 PAC:20198128 Eutrema salsugineum 480  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10376820
            8606150
            15226302
            10931835
            2166030
            18263721