Protein Domain : IPR000905

Type:  Domain Name:  Gcp-like domain
Description:  This domain was identified in proteins including Kae1 and Gcp (YgjD), which were originally thought to be endopeptidases belonging to the peptidase M22 family []. However, there is a lack of experimental evidence to support peptidase activity as a general property, and this has not been confirmed in other orthologues [, ]. Recent research indicates that the Kae1 and Gcp proteins are involved in the biosynthesis of N6-threonylcarbamoyl adenosine, a universal modification found at position 37 of tRNAs that read codons beginning with adenine []. This domain is also present in Bacillus subtilis YdiC and Escherichia coli YeaZ. These proteins have been recently renamed as TsaB, and have also been shown to be involved in N6-Threonylcarbamoylad enonsine (t(6)A) biosynthesis [, ]. Short Name:  Gcp-like_dom
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0 Child Features

1 Contains

DB identifier Type Name
IPR017860 Conserved_site Peptidase M22, conserved site

1 Cross References

Identifier
PF00814

1 Found In

DB identifier Type Name
IPR009220 Family Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
178622 D8SCG1 PAC:15408513 Selaginella moellendorffii 337  
120984 D8SN57 PAC:15418614 Selaginella moellendorffii 431  
evm.model.supercontig_18.102 PAC:16411241 Carica papaya 480  
evm.model.supercontig_9.295 PAC:16428196 Carica papaya 281  
30174.m008855 B9RD99 PAC:16822500 Ricinus communis 455  
29569.m000149 B9T542 PAC:16803025 Ricinus communis 346  
Cucsa.011070.1 PAC:16951366 Cucumis sativus 352  
Cucsa.011070.2 PAC:16951367 Cucumis sativus 252  
Cucsa.257530.1 PAC:16972721 Cucumis sativus 332  
orange1.1g018903m A0A067DQP4 PAC:18119336 Citrus sinensis 349  
orange1.1g039172m A0A067H1S6 PAC:18136959 Citrus sinensis 477  
AT4G22720.2 O49653 PAC:19645090 Arabidopsis thaliana 353  
AT4G22720.1 O49653 PAC:19645089 Arabidopsis thaliana 353  
AT2G45270.1 O22145 PAC:19640156 Arabidopsis thaliana 480  
Thhalv10025586m V4MF49 PAC:20192925 Eutrema salsugineum 352  
Thhalv10001427m V4LHB3 PAC:20188768 Eutrema salsugineum 481  
Ciclev10002827m V4T544 PAC:20788118 Citrus clementina 132  
Ciclev10001634m V4SV63 PAC:20787772 Citrus clementina 357  
Ciclev10001681m V4T536 PAC:20787773 Citrus clementina 349  
Ciclev10021173m V4VYI3 PAC:20808668 Citrus clementina 322  
Lus10030285 PAC:23153186 Linum usitatissimum 399  
Lus10000791 PAC:23168864 Linum usitatissimum 460  
Lus10029108 PAC:23151775 Linum usitatissimum 195  
Potri.T124300.1 A0A2K1R5X1 PAC:27000445 Populus trichocarpa 242  
Potri.017G029200.1 PAC:26984341 Populus trichocarpa 389  
Potri.017G029200.3 B9MY43 PAC:26984343 Populus trichocarpa 360  
Potri.017G029200.4 B9MY43 PAC:26984344 Populus trichocarpa 360  
Potri.017G029200.2 B9MY43 PAC:26984342 Populus trichocarpa 360  
Potri.007G129400.1 A0A2K1ZTL3 PAC:27015553 Populus trichocarpa 139  
Potri.014G067800.2 PAC:27034422 Populus trichocarpa 348  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1885539
            17766251
            21183954
            21285948
            22378793
            23072323