Protein Domain : IPR014358

Type:  Family Name:  Enoyl-[acyl-carrier-protein] reductase (NADH)
Description:  This entry contains enoyl-[acyl-carrier-protein] reductases (). They are components of the type II (dissociable) fatty acid synthase system and catalyse the terminal reaction in the fatty acid elongation cycle.They belong to the short-chain dehydrogenases/reductases (SDR) domain superfamily [, , ] and are therefore related to members of -, amongst others.Most SDRs contain two subdomains. The N-terminal subdomain binds the coenzyme, and the C-terminal subdomain binds the substrate, determines the substrate specificity and contains amino acids involved in catalysis [, , ]. Despite low sequence similarity, all SDR structures display highly similar alpha/beta folding patterns with a central beta-sheet, typical of the Rossmann-fold [].Crystal structures of these proteins have been extensively studied [, , , , , , ].(This information was partially derived from the PFAM database, ) Short Name:  Enoyl-ACP_Rdtase_NADH
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0 Child Features

1 Contains

DB identifier Type Name
IPR016040 Domain NAD(P)-binding domain

1 Cross References

Identifier
PIRSF000094

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004318 IPR014358
GO:0006633 IPR014358
GO:0055114 IPR014358

3 Ontology Annotations

GO Term Gene Name
GO:0004318 IPR014358
GO:0006633 IPR014358
GO:0055114 IPR014358

1 Parent Features

DB identifier Type Name
IPR002347 Family Glucose/ribitol dehydrogenase

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Traes_5DL_D3AA8B440.4 PAC:31803237 Triticum aestivum 230  
Traes_7AL_3A910D814.4 PAC:31872718 Triticum aestivum 230  
Traes_7DL_09D23CBAF.2 PAC:31976396 Triticum aestivum 230  
Pp3s70_130V3.1.p PAC:32963353 Physcomitrium patens 257  
HORVU7Hr1G085220.13 PAC:38551894 Hordeum vulgare 230  

10 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7742302
            8535786
            9417034
            10595560
            12109908
            12699381
            10398587
            10493822
            12604213
            12604210