GO Term : GO:1902450 negative regulation of ATP-dependent DNA helicase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

74 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0016887 ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0003678 DNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
GO:0008026 ATP-dependent helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0008094 DNA-dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0004386 helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO:0004003 ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0051276 chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0042623 ATPase activity, coupled Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0032508 DNA duplex unwinding The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0032780 negative regulation of ATPase activity Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.

114 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
negatively regulates GO:0004003 GO:1902450
is_a GO:0032780 GO:1902450
is_a GO:2001251 GO:1902450
negatively regulates GO:0004003 GO:1902450
is_a GO:1902449 GO:1902450
is_a GO:0051053 GO:1902450
is_a GO:0051097 GO:1902450
is_a GO:0065007 GO:1902450
regulates GO:0006259 GO:1902450
regulates GO:0006139 GO:1902450
is_a GO:0050790 GO:1902450
negatively regulates GO:0051276 GO:1902450
is_a GO:0050794 GO:1902450
negatively regulates GO:1901360 GO:1902450
negatively regulates GO:0046483 GO:1902450
is_a GO:0051129 GO:1902450
negatively regulates GO:0016787 GO:1902450
is_a GO:0051128 GO:1902450
regulates GO:0008152 GO:1902450
regulates GO:0008150 GO:1902450
regulates GO:0016462 GO:1902450
regulates GO:0090304 GO:1902450
regulates GO:0042623 GO:1902450
is_a GO:0065007 GO:1902450
is_a GO:0065009 GO:1902450
regulates GO:0071103 GO:1902450
regulates GO:0006807 GO:1902450
regulates GO:0032392 GO:1902450
is_a GO:0051095 GO:1902450
regulates GO:0004003 GO:1902450

4 Synonyms

Name Type
inhibition of ATP-dependent DNA helicase activity synonym
down regulation of ATP-dependent DNA helicase activity synonym
downregulation of ATP-dependent DNA helicase activity synonym
down-regulation of ATP-dependent DNA helicase activity synonym