GO Term : GO:0039567 suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus GO
Namespace:  biological_process Obsolete:  false
description  Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

125 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0006606 protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.
GO:0006605 protein targeting The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0006886 intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035556 intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GO:0006913 nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm.
GO:0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0017038 protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0016032 viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0019048 modulation by virus of host morphology or physiology The process in which a virus effects a change in the structure or processes of its host organism.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:1902580 single-organism cellular localization A cellular localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.

180 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1903652 GO:0039567
is_a GO:1990215 GO:0039567
is_a GO:0044833 GO:0039567
is_a GO:0039563 GO:0039567
is_a GO:2000365 GO:0039567
part of GO:0044403 GO:0039567
negatively regulates GO:0008104 GO:0039567
negatively regulates GO:0007259 GO:0039567
is_a GO:0044092 GO:0039567
regulates GO:0006913 GO:0039567
regulates GO:0007165 GO:0039567
is_a GO:0008150 GO:0039567
regulates GO:0009987 GO:0039567
is_a GO:0019048 GO:0039567
negatively regulates GO:0015031 GO:0039567
negatively regulates GO:0016482 GO:0039567
negatively regulates GO:0071702 GO:0039567
regulates GO:1902593 GO:0039567
negatively regulates GO:0046907 GO:0039567
is_a GO:0044419 GO:0039567
negatively regulates GO:0006606 GO:0039567
is_a GO:0051224 GO:0039567
is_a GO:0052038 GO:0039567
negatively regulates GO:0006605 GO:0039567
is_a GO:0090317 GO:0039567
negatively regulates GO:0072594 GO:0039567
regulates GO:0051169 GO:0039567
is_a GO:0032387 GO:0039567
part of GO:0008150 GO:0039567
is_a GO:0032386 GO:0039567

2 Synonyms

Name Type
cytoplasmic sequestration of STAT1 synonym
suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1 synonym